PMID: 3746308Jul 1, 1986Paper

Pupil cycle time: a simple way of measuring an autonomic reflex

Journal of Neurology, Neurosurgery, and Psychiatry
C N Martyn, D J Ewing

Abstract

Persistent regular oscillations of the pupil of the eye can be induced using a slit-lamp. The period of these oscillations, pupil cycle time (PCT), is simple to measure with a hand-held stop-watch. Evidence from pharmacological testing suggests that PCT is a sensitive measure of dysfunction of the parasympathetic efferent limb of the pupillary light reflex arc. This is confirmed by the finding that PCT is prolonged in a high proportion of patients with evidence of autonomic neuropathy judged by abnormalities of their cardiovascular reflexes. The method provides a simple, non-invasive way of quantifying an autonomic reflex and it may be of value in investigating patients with diseases affecting the autonomic nervous system.

References

Jul 1, 1978·The British Journal of Ophthalmology·S D Miller, H S Thompson
Sep 30, 1978·British Medical Journal·S E SmithP H Sönksen
Jan 1, 1977·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·T FujiiS Uga
Nov 1, 1967·Annals of Internal Medicine·S A FriedmanR H Bedell
Oct 2, 1982·British Medical Journal·D J Ewing, B F Clarke
Feb 1, 1983·The British Journal of Ophthalmology·S A Smith, S E Smith
Oct 1, 1982·Archives of Ophthalmology·T A CoxJ E Snyder
Jun 1, 1944·The British Journal of Ophthalmology·H J Stern

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Citations

Apr 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·C V Clark
Dec 1, 1988·Documenta Ophthalmologica. Advances in Ophthalmology·C V Clark, D J Ewing
Jan 1, 1986·Documenta Ophthalmologica. Advances in Ophthalmology·C V Clark, R Mapstone
Oct 15, 2008·International Urology and Nephrology·Rusen DundarozEmre Tascilar
Jan 1, 1990·Vision Research·J G Milton, A Longtin
Jan 1, 1997·Journal of Diabetes and Its Complications·K D ModiA Mithal
Jan 1, 1989·Eye·D J Brazier
May 1, 1995·Acta Neurologica Scandinavica·G MicieliG Nappi
May 19, 2011·Indian Journal of Ophthalmology·Hoyoung LeeJongseok Park
Nov 5, 2013·BioMed Research International·L MesinR Cattaneo
Dec 1, 1994·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·M De Marinis
Jan 1, 1988·Medical & Biological Engineering & Computing·J P ReulenK Boshuizen
Jul 1, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·P MoonR P Taylor
Jan 1, 1993·Diabetes Research and Clinical Practice·A de VosH Schneider
Sep 27, 2000·Journal of Manipulative and Physiological Therapeutics·P F GibbonsM Holmes
Dec 8, 2006·Physiological Measurement·A HacholD Wygledowska-Promienska
Mar 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·J P HeathR E Cull
Jan 3, 2020·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Melissa M CortezCorey L Campbell
Oct 29, 1997·International Journal of Radiation Biology·F Ianzini, M A Mackey
Nov 1, 1991·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·A MurrayR H Clayton
May 1, 1996·International Journal of Radiation Biology·T J Jorgensen, Y Shiloh
Oct 1, 2020·Journal of Adolescent and Young Adult Oncology·Sudhashini ChandrasekaranTengku Ain Kamalden
Jun 20, 2003·European Journal of Clinical Investigation·E O SanyaM J Hilz
May 30, 2019·Frontiers in Neurology·Melissa M CortezK C Brennan
Mar 25, 2020·Diabetology International·Hideyuki SasakiPhillip A Low
May 17, 2007·Arquivos brasileiros de endocrinologia e metabologia·Helena Schmid
Mar 20, 2021·Physiological Measurement·Susmit BhowmikDinesh K Kumar
Nov 1, 1986·Clinics in Endocrinology and Metabolism·D J Ewing, B F Clarke

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