Pure Immature Teratoma of the Ovary in Adults: Thirty-Year Experience of a Single Tertiary Care Center

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Ahmad Bakr AlwazzanAlon D Altman

Abstract

The aim of this study was to evaluate clinicopathologic characteristics, treatment outcome, and reproductive function in women diagnosed with ovarian immature teratoma (IT). Our standard chemotherapy regime is currently etoposide/cisplatin (EP), creating a unique opportunity to evaluate this protocol in ovarian ITs. This study is a retrospective analysis. Twenty-seven women older than 18 years with ovarian IT stages IA to IIIC were identified and included in this study. Patients were treated at 1 institution, Health Sciences Center, Women's Hospital, Winnipeg, Manitoba, Canada, between 1983 and 2013. The median age at diagnosis was 27.0 years (range, 18-36 years). Twenty-two (82%) presented with an International Federation of Gynecology and Obstetrics stage I disease, 3 (11%) had stage II, and 2 patients (7%) had stage III disease. The histologic grade distribution was grade I in 9 patients (33%), grade II in 3 patients (11%), and grade III in 15 patients (56%). Initial management was surgical for all patients: 3 (11%) hysterectomy and bilateral salpingo-oophorectomy, 1 (4%) cystectomy only, and 23 (85%) unilateral salpingo-oophorectomy. Twenty-one patients (78%) received adjuvant therapy. The median follow-up was 60 months (ra...Continue Reading

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Citations

Sep 1, 2017·Journal of Pediatric Hematology/oncology·Cécile Faure-Conter, Farzana Pashankar
Apr 19, 2019·Journal of Cancer Survivorship : Research and Practice·Brigitte GerstlAntoinette Anazodo
Apr 19, 2017·The Journal of International Medical Research·Ting ZhaoYuan Lu
Mar 16, 2017·Case Reports in Obstetrics and Gynecology·Daisuke ShigemiToshiyuki Takeshita
Dec 18, 2019·Histopathology·Daniel M BerneyMichelle Lockley
Jun 13, 2020·Ultrasound : Journal of the British Medical Ultrasound Society·S Abdullahi IdleJ A Ross
Mar 24, 2021·International Journal of Surgery Case Reports·Jignesh RathodJay Chotaliya

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Methods Mentioned

BETA
surgical resection

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