Purification and Characterization of a Proteasome from the Hyperthermophilic Archaeon Pyrococcus furiosus.

Applied and Environmental Microbiology
M W BauerR M Kelly

Abstract

A 640-kDa proteasome consisting of (alpha) (25-kDa) and (beta) (22-kDa) subunits, and with a temperature optimum of 95(deg)C, was purified from crude cell extracts of a hyperthermophilic archaeon, Pyrococcus furiosus. Although this is the fourth member of the kingdom Euryarchaeota (and the first hyperthermophile) found to contain a proteasome, none has been identified among the members of the kingdom Crenarchaeota.

References

Jun 4, 1992·Nature·A L Goldberg, K L Rock
Sep 15, 1992·European Journal of Biochemistry·B DahlmannW Baumeister
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·C R WoeseM L Wheelis
Dec 1, 1995·The Journal of Biological Chemistry·J A Maupin-Furlow, J G Ferry
Nov 1, 1994·Nature Structural Biology·P ZwicklW Baumeister
Jan 1, 1993·Enzyme & Protein·N TanahashiK Tanaka
Apr 28, 1995·Science·E SeemüllerW Baumeister
Dec 1, 1994·Trends in Biochemical Sciences·A LupasW Baumeister
Aug 1, 1994·European Journal of Biochemistry·A GrziwaR Jaenicke
Apr 1, 1992·Applied and Environmental Microbiology·L J SnowdenR M Kelly

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Citations

Oct 31, 2019·Biological Chemistry·Parijat Majumder, Wolfgang Baumeister
Jan 29, 2000·Molecular Microbiology·M N PouchW Baumeister
Apr 5, 2003·Applied and Environmental Microbiology·Keith R ShockleyRobert M Kelly
Jun 29, 2000·Annual Review of Biochemistry·D VogesW Baumeister
Mar 28, 2002·Physiological Reviews·Michael H Glickman, Aaron Ciechanover
Oct 10, 1998·Journal of Bacteriology·I NagyR De Mot
Feb 17, 2017·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·James A CountsRobert M Kelly
Dec 1, 2018·Emerging Topics in Life Sciences·Julie A Maupin-Furlow
Sep 2, 2003·Metabolic Engineering·Julie A Maupin-FurlowMalgorzata A Gil
Dec 31, 1997·Microbiology and Molecular Biology Reviews : MMBR·J R Brown, W F Doolittle

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