Purification and partial characterization of a type-specific antigen of Rickettsia tsutsugamushi.

Infection and Immunity
N OhashiK Hayashi

Abstract

A type-specific antigen (54- to 56-kilodalton polypeptide) in the envelope of Rickettsia tsutsugamushi was purified from each of three prototype strains (Gilliam, Karp, and Kato) by a combination of mild anionic detergent treatment, gel filtration, and reverse-phase high-performance liquid chromatography. The purified antigens from the three strains were shown to have similar amino acid compositions: primarily aspartic acid, glutamic acid, and glycine, with lesser amounts of cysteine, methionine, and tyrosine. The N-terminal amino acid sequences of the antigens were 74.3% homologous among the three strains.

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Citations

May 1, 1991·European Journal of Epidemiology·A TamuraN Ohashi
Sep 3, 2010·The American Journal of Tropical Medicine and Hygiene·Hsiu-Ying LuPei-Yun Shu
Feb 5, 2011·The American Journal of Tropical Medicine and Hygiene·Yu-Mi LeeGanesh Prasad Neupane
May 10, 2003·Clinical and Diagnostic Laboratory Immunology·Won-Jong JangIk-Sang Kim
Jan 1, 1997·Microbiology and Immunology·S Y SeongW H Chang
Jul 26, 2005·Infection and Immunity·Suchismita ChattopadhyayAllen L Richards
Feb 28, 2001·Microbes and Infection·S Y SeongI S Kim
Jan 19, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Veasna DuongPhilippe Buchy
Jun 30, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Patimaporn WongprompitakYupin Suputtamongkol

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