PMID: 6973604Aug 1, 1981Paper

Purification of murine T cell growth factor. A lymphocyte mitogen with helper activity

The Journal of Experimental Medicine
A Granelli-PipernoE Reich

Abstract

Mouse T cell growth factor was purified from the serum-free conditioned medium of lectin-stimulated spleen cells. A 3,000-fold purification was achieved with a final yield of 12%. The purified protein, with an apparent Mr of 23,000 by sodium dodecyl sulfate polyacrylamide gel electrophoresis, was active at concentrations of 4 x 10(-11) M, both in the T cell growth factor and T cell replacing factor assays. In addition, purified T cell growth factor alone was mitogenic for spleen cells from both nude and normal mice.

References

Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C R MerrilM L Van Keuren
Jul 14, 1977·Nature·S Gillis, K A Smith
Jun 1, 1979·The Journal of Experimental Medicine·S GillisK A Smith
Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·D W TalmageK J Lafferty
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Oct 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J W Mier, R C Gallo

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Citations

Jan 1, 1983·Cancer Immunology, Immunotherapy : CII·J BubeníkJ Neuwirt
Jan 1, 1982·Journal of Immunological Methods·B Sredni
Oct 24, 1985·Journal of Immunological Methods·A J GearingR Thorpe
Jan 1, 1985·Developmental and Comparative Immunology·D Watkins, N Cohen
Sep 1, 1984·Veterinary Immunology and Immunopathology·M Miller-Edge, G A Splitter
Feb 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·A S SternS Gillis
Mar 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·C CernettiA Granelli-Piperno
Aug 1, 1982·The Journal of Experimental Medicine·K WelteM A Moore
Apr 1, 1983·The Journal of Experimental Medicine·J M AustynM A Palladino
Dec 1, 1983·The Journal of Experimental Medicine·N NogueiraR Steinman
Feb 1, 1984·The Journal of Experimental Medicine·L AndrusE Reich
Sep 1, 1984·The Journal of Experimental Medicine·A Granelli-PipernoE Reich
Dec 1, 1984·The Journal of Experimental Medicine·A Granelli-PipernoR M Steinman
Apr 1, 1989·Scandinavian Journal of Immunology·L Hadjipetrou-KourounakisP Kourounakis
Aug 31, 1992·Biochemical and Biophysical Research Communications·K N Balaji, R Nayak
Dec 24, 1981·Nature·W E PaulR H Schwartz
Jan 1, 1985·Journal of Immunopharmacology·A E ChangS A Rosenberg
May 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hans DoomsAbul K Abbas

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