PMID: 435493Mar 23, 1979Paper

Purification of the cytochalasin B binding component of the human erythrocyte monosaccharide transport system

Biochimica Et Biophysica Acta
S A BaldwinG E Lienhard


The cytochalasin B binding component of the human erythrocyte monosaccharide transport system has been purified. The preparation appears to contain one major protein with an apparent polypeptide chain molecular weight of 55,000 and about 0.4 binding sites per chain. Cytochalasin B binds to the reconstituted preparation with a dissociation constant of 1.3.10(-7) M, a value which is similar to that reported for the transport system in the intact erythrocyte.


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