PMID: 44605Oct 1, 1979

Purine nucleoside triphosphates in Streptomyces hydrogenans. Influence of steroids on the relative nucleotide level

Zentralblatt Für Bakteriologie, Parasitenkunde, Infektionskrankheiten Und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie Und Parasitologie
M Vogel, L Träger

Abstract

Various steroids in the culture medium of Streptomyces hydrogenans cause a rapid decrease of the relative GTP content of the cells. The relative ATP level is significantly diminished in the presence of progesterone and testosterone acetate. The initial decrease of the relative GTP content is proportional to the growth inhibitory effect of the steroids tested. There is no relationship between steroid-dependent induction of the synthesis of 20 beta- and 17 beta-hydroxysteroid dehydrogenase and the ability of the steroids to decrease the relative GTP content of the cells.

Related Concepts

Adenosine Triphosphate, Chromium Ammonium Salt
Enzyme Induction
Guanosine Triphosphate
Progesterone, (9 beta,10 alpha)-Isomer
Purine Nucleotides
Streptomyces
Sterotate
17 beta-Hydroxysteroid Dehydrogenases
20-Hydroxysteroid Dehydrogenases

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