PMID: 5903589Feb 4, 1966

Puromycin effect on successive phases of memory storage

Science
S H Barondes, H D Cohen

Abstract

Mice injected bitemporally with puromycin 5 hours before training learned to escape or to avoid shock by choosing the correct limb of a Y-maze. When retested 15 minutes after training they had normal retention. In the ensuing 2(3/4) hours the animals injected with puromycin, unlike the controls, showed a progressive decrease of savings to less than 7 percent.

Citations

Mar 1, 1974·Behavior Genetics·L L UphouseK Schlesinger
Apr 13, 1973·Brain Research·J Gervai, V Csányi
Dec 1, 1970·Comparative and General Pharmacology·G A KerkutR J Walker
Dec 1, 1966·Journal of Psychiatric Research·W W Meissner
Jul 1, 1973·Physiology & Behavior·J MajkowskiD Chadzypanagiotis
Apr 1, 1973·Physiology & Behavior·J van AbeelenG Douma
Nov 1, 1973·Pharmacology, Biochemistry, and Behavior·W G Braud, W J Broussard
Mar 1, 1977·Pharmacology, Biochemistry, and Behavior·D Kobiler, C Allweis
Jan 1, 1975·Progress in Neurobiology·I Izquierdo
Jan 1, 1979·General Pharmacology·G W OliverB H Livett
Jun 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·J W ZempE Glassman
Aug 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·L B FlexnerR B Roberts
Jun 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·J B Flexner, L B Flexner
Jul 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·S H Barondes, H D Cohen
Feb 1, 1968·The Journal of Cell Biology·P GambettiL B Flexner
Aug 20, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jaehoon ShinHongjun Song
Dec 7, 2007·Neurobiology of Learning and Memory·Pepe J Hernandez, Ted Abel
Sep 1, 1974·Behavioral Biology·G L WilcoxM W Luttges
Aug 1, 1966·Experimental Parasitology·L J Olson, J E Rose
Oct 1, 1967·Brain Research·B M Brown, E P Noble
Oct 7, 2015·Frontiers in Molecular Neuroscience·Verónica de la FuenteArturo Romano
Nov 28, 2013·The Quarterly Journal of Experimental Psychology : QJEP·Raquel Cocenas-SilvaSylvie Droit-Volet
Jan 20, 1968·Nature·V E Shashoua
Sep 10, 1966·Nature·J S Griffith
Sep 28, 1971·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M E Watts, R F Mark
Sep 1, 1968·Journal of Mental Deficiency Research·R GunterW J Brown
Mar 17, 2019·Proceedings of the National Academy of Sciences of the United States of America·André F de SousaMark Mayford
May 1, 1969·Quarterly Reviews of Biophysics·R B Roberts, L B Flexner
Apr 25, 2020·Science·Mauro Costa-Mattioli, Peter Walter

Related Concepts

Avoidance Learning
Behavior, Animal
Memory
Psychopharmacology
Puromycin Dihydrochloride

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
L B Flexner, J B Flexner
Proceedings of the National Academy of Sciences of the United States of America
B W AgranoffJ J Brink
© 2021 Meta ULC. All rights reserved