Abstract
Introduction: Hypotension is a critical event during the transport of critically ill patients. Push dose vasopressor use, though widely adopted by anesthesiologists, has only recently found use in the field of emergency medicine and may have utility in the management of out-of-hospital hypotension. This study aimed to characterize the hemodynamic effects and adverse events that occur following push dose epinephrine (PDE) administration by critical care transport (CCT) providers to correct documented hypotension. Methods: We performed a retrospective observational study of patients transported by a regional critical care transport service and who received PDE during transport to correct documented hypotension. Per protocol, 10-20 µg of 1:100,000 epinephrine was given intravenously every 2 min until: (1) the systolic blood pressure (SBP) was at least 90 mmHg, or (2) the mean arterial pressure (MAP) was 65 mmHg or greater. All patients were over 18 years of age and were transported between January 1, 2015 and December 31, 2016. Primary outcomes of interest were the primary diagnoses associated with PDE use, hemodynamic outcomes of the intervention, and adverse events. Results: During the study period 100 doses of push dose epineph...Continue Reading
References
Mar 28, 2002·Anesthesia and Analgesia·Anna LeeTony Gin
Jun 6, 2009·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Jeffrey M SinghMichael J Schull
Sep 16, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Jeffrey M SinghMichael J Schull
Oct 30, 2009·Critical Care Medicine·Stephen TrzeciakJoseph E Parrillo
Dec 25, 2009·Annals of Emergency Medicine·Manreet KanwarHoward Rosman
May 21, 2010·Resuscitation·A HartkeF X Guyette
Jan 29, 2013·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
Dec 18, 2013·Resuscitation·Janet E BrayUNKNOWN VACAR Steering Committee
Jan 15, 2014·Annals of Emergency Medicine·Jeffrey M SinghMahvareh Ahghari
Jun 3, 2014·Critical Care : the Official Journal of the Critical Care Forum·Vance BeckUNKNOWN Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group
Jan 13, 2015·The Journal of Allergy and Clinical Immunology. in Practice·Ronna L CampbellErik P Hess
Feb 12, 2015·Journal of Critical Care·Osama M Loubani, Robert S Green
Mar 25, 2015·Critical Care Medicine·Khalid AlmahmoudYoram Vodovotz
May 28, 2015·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Jose Cardenas-GarciaPaul H Mayo
Jun 25, 2015·The Journal of Emergency Medicine·Ashish R PanchalJarrod Mosier
Oct 17, 2015·Circulation·Clifton W CallawayJanice L Zimmerman
May 10, 2016·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Lauren J Tilton, Kristin H Eginger
Oct 11, 2016·The American Journal of Emergency Medicine·Madison B SchwartzPatrick M Aaronson
Jun 30, 2015·Clinical and Experimental Emergency Medicine·Scott Weingart
Mar 2, 2017·Anesthesia and Analgesia·Desire N OnwocheiJose C A Carvalho
Jun 12, 2017·Annals of Emergency Medicine·Devin HoldenTimothy Lesar
Jun 20, 2017·The American Journal of Emergency Medicine·Nicole M AcquistoChristine Johnstone
Jul 30, 2017·Annals of Emergency Medicine·Jon B Cole
Sep 6, 2017·Anesthesiology·Warwick D Ngan Kee
Jan 11, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Pamela D ReiterLeslie A Ridall
Feb 27, 2018·Air Medical Journal·Aurore RichardDaniel Davis
Citations
Jul 18, 2019·The Journal of International Medical Research·Mohammed A Al-MulhimLayla B Al-Qahtani
Mar 3, 2020·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Andrew D FisherSteven G Schauer
Jul 24, 2020·Prehospital and Disaster Medicine·Casey PatrickRobert Dickson
Jul 14, 2020·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Christopher CliffordAlex F Manini
Jul 5, 2019·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Jon B ColeBrian E Driver
Oct 22, 2020·Circulation·Ashish R PanchalUNKNOWN Adult Basic and Advanced Life Support Writing Group
Jul 6, 2021·The American Journal of Emergency Medicine·Francisco Martín-RodríguezRaúl López-Izquierdo
Jun 19, 2021·The American Journal of Emergency Medicine·Jeremy LacocqueKarl A Sporer
Jul 25, 2021·The American Journal of Emergency Medicine·Kyle A Weant, David M French
Sep 11, 2021·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Romain Jouffroy, Benoît Vivien
Jan 11, 2022·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Daniel P DavisMichael Levy