Putative virulence-related genes in Vibrio anguillarum identified by random genome sequencing

Journal of Fish Diseases
C RodkhumT Aoki

Abstract

The genome of Vibrio anguillarum strain H775-3 was partially determined by a random sequencing procedure. A total of 2,300 clones, 2,100 from a plasmid library and 200 from a cosmid library, were sequenced and subjected to homology search by the BLAST algorithm. The total length of the sequenced clones is 1.5 Mbp. The nucleotide sequences were classified into 17 broad functional categories. Forty putative virulence-related genes were identified, 36 of which are novel in V. anguillarum, including a repeat in toxin gene cluster, haemolysin genes, enterobactin gene, protease genes, lipopolysaccharide biosynthesis genes, capsule biosynthesis gene, flagellar genes and pilus genes.

References

Mar 1, 1987·American Heart Journal·K Ausubel, B Gitler
Jan 1, 1996·Infection and Immunity·M E Bauer, R A Welch
Mar 1, 1996·Journal of Bacteriology·D L MiltonH Wolf-Watz
Sep 1, 1996·Microbial Pathogenesis·I HironoT Aoki
Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·M TrucksisJ B Kaper
Feb 3, 1999·Proceedings of the National Academy of Sciences of the United States of America·W LinJ J Mekalanos
Sep 2, 1999·Trends in Microbiology·E T LallyJ Korostoff
Jul 11, 2001·FEMS Microbiology Letters·T M Wassenaar, W Gaastra
Jul 27, 2002·Journal of Bacteriology·Kenichi TagomoriTakeshi Honda
Dec 4, 2002·Plasmid·Michiel StorkJorge H Crosa
Dec 6, 2003·Genome Research·Chung-Yung ChenShih-Feng Tsai
Jul 9, 2004·Applied and Environmental Microbiology·Steven M Denkin, David R Nelson
Dec 14, 2004·Journal of Microbiological Methods·Gareth Lloyd-JonesAynsley C Tizzard
Jan 5, 2005·Journal of Bacteriology·Kazuhisa OkadaTakeshi Honda
Feb 11, 2005·Proceedings of the National Academy of Sciences of the United States of America·E G RubyE P Greenberg
Aug 30, 2005·Microbial Pathogenesis·Channarong RodkhumTakashi Aoki
Sep 15, 2005·Journal of Microbiological Methods·Sankar DasTodd Kitten
Feb 12, 2008·Current Protocols in Molecular Biology·S Tabor

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Citations

Jun 1, 2011·Fish Pathology·Hiroaki Naka, Jorge H Crosa
Apr 11, 2008·Journal of Fish Diseases·C RodkhumT Aoki
Sep 6, 2014·Frontiers in Microbiology·Thomas M LuxJohn Love
Jan 15, 2008·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Craig R WardenMohamud Daya
Aug 16, 2011·Journal of Fish Diseases·I FransH Rediers
Oct 12, 2019·Scientific Reports·Veronica BatallonesMarcelo E Tolmasky

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