Putting a finger on potential predictors of oral contraceptive side effects: 2D:4D and middle-phalangeal hair

Psychoneuroendocrinology
Kirsten A Oinonen

Abstract

Many women experience emotional or physical side effects when taking oral contraceptives (OCs). Despite the potential impact on women's health and well-being, there are no valid methods to screen women for their risk of OC side effects. The present paper presents the results of two studies where anthropometric indicators of androgen exposure, 2D:4D and middle-phalangeal hair, were examined for their potential as predictors of OC side effects. In study 1, 2D:4D was associated with women's reports of a history of: (a) negative mood side effects; (b) discontinuation due to negative mood side effects; (c) specific mood side effects (i.e., crying, sadness, and altered trust in one's partners) and (d) specific physical side effects (i.e., headaches, fatigue, and decreased sex drive). In study 2, 2D:4D and/or middle-phalangeal hair was/were associated with a reported history of: (a) discontinuation due to negative mood side effects; (b) specific mood-related side effects (i.e., negative mood, disrupted sleep, increased aggression, and altered trust in one's partner) and (c) specific physical side effects (i.e., headaches, decreased menstrual cramps, and increased sex drive/arousal). The general pattern was that adverse OC side effects...Continue Reading

References

Nov 1, 1975·American Journal of Physical Anthropology·S M GarnS Stinson
May 1, 1992·American Journal of Physical Anthropology·R KnussmannJ Kannmacher
May 1, 1986·Clinics in Endocrinology and Metabolism·V Toscano
Sep 1, 1972·The Journal of Nervous and Mental Disease·S J Kutner, W L Brown
Oct 1, 1993·American Journal of Physical Anthropology·E M Winkler, K Christiansen
Mar 16, 2000·Contraception·I H ThorneycroftM E Weber
Jul 20, 2002·Journal of Affective Disorders·Kirsten A Oinonen, Dwight Mazmanian
Sep 1, 1951·American Journal of Physical Anthropology·S M GARN
Dec 29, 2004·Biological Psychology·Allison A Bailey, Peter L Hurd
Jun 23, 2005·American Journal of Obstetrics and Gynecology·Terry WhiteFrank Z Stanczyk
Dec 20, 2005·Fertility and Sterility·Fleur R CattrallGareth C Weston
Feb 14, 2006·Early Human Development·Mehmet Ali MalasKadir Desdicioglu
Aug 24, 2007·Archives of Women's Mental Health·J A Jarva, K A Oinonen
Oct 19, 2007·Archives of Sexual Behavior·Milagros Evardone, Gerianne M Alexander
Dec 14, 2007·Archives of Sexual Behavior·Elizabeth HampsonChristine M Tenk
Jan 19, 2008·American Journal of Human Biology : the Official Journal of the Human Biology Council·Loretta BrabinHenry C Kitchener
Apr 29, 2008·Hormones and Behavior·Hans VermeerschJ Vincke
Jan 1, 2008·Personality and Individual Differences·Milagros EvardoneLeslie C Morey

❮ Previous
Next ❯

Citations

Jul 5, 2011·Archives of Women's Mental Health·Jessica L Bird, Kirsten A Oinonen
Apr 12, 2013·Journal of Autism and Developmental Disorders·Missy L Teatero, Charles Netley
Aug 28, 2009·Psychological Reports·Martin Voracek, Lisa Mariella Loibl
Jan 29, 2011·Hormones and Behavior·J Bancroft, C A Graham
Dec 3, 2010·Journal of Cosmetic Dermatology·Adaeze Egesi, Rashid Rashid
Apr 18, 2015·Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen·N WestlundJ L Bird
Sep 17, 2016·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Jonathan SchaffirTamar L Gur
Jan 21, 2017·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Els Elaut

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.