PMID: 8615336Mar 1, 1996Paper

Putting body weight and osteoporosis into perspective

The American Journal of Clinical Nutrition
G Wardlaw

Abstract

Osteoporosis is characterized by a reduction in bone mineral density (BMD). Women more than men are at risk for osteoporosis-related fractures, especially in the wrists, lumbar spine, and hips. Numerous diet and lifestyle factors, including body weight, influence BMD, and in turn, fracture risk. BMD in the total body, hip, lumbar spine, and radius is weakly to moderately correlated to body weight, fat mass, and lean body mass in adolescent, perimenopausal, and elderly women, possibly as the result of stress on the skeleton from the mechanical loading of body weight alone. In addition, greater lean body mass may be a cause. Other explanations include increased hormonal circulation in obese women and greater conversion of adrenal androgens to estrogens linked to greater mass of adipose tissue. Currently no value is agreed on for weight-to-height versus osteoporosis and related fracture risk, but some extra fat mass yielding a body mass index > 26-28 does confer limited protection, whereas a slender figure yielding a body mass index < 22-24 increases risk.

Citations

Jan 1, 1997·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M FogelholmI Vuori
Mar 27, 2001·Journal of Women's Health & Gender-based Medicine·G A KuchelN M Resnick
Mar 5, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Claudia S RiedtSue A Shapses
Mar 23, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·X FuS Zhu
Sep 26, 2013·Aging Clinical and Experimental Research·Silvia MigliaccioAndrea Lenzi
Oct 12, 2013·Journal of Bone and Mineral Metabolism·Wankyo ChungOhk-Hyun Ryu
Jun 6, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T D CunninghamJ Ullal
Jun 15, 2018·Haemophilia : the Official Journal of the World Federation of Hemophilia·C L Sossa MeloC M Chalela
Jun 11, 2020·JAMA Network Open·Syed I KhalidAlfonso Torquati
Apr 2, 2002·Journal of the American Academy of Nurse Practitioners·Janice J TwissAudrey Paulman
May 3, 2007·The Journal of Clinical Endocrinology and Metabolism·Zi-Hui TangHong-Wen Deng
Oct 24, 2007·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Farsad AfshinniaTooraj Zahedi
Aug 13, 2008·Expert Opinion on Investigational Drugs·Simon GrahamEleftherios Tsiridis
Jul 16, 2010·Calcified Tissue International·Han Seok ChoiSung-Kil Lim
Oct 19, 2010·Journal of Epidemiology·Dong-Hun LeeJoohon Sung
Dec 23, 2011·Age·Ricki J ColmanRichard Weindruch
Oct 19, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J H KimN H Cho
May 6, 2011·CA: a Cancer Journal for Clinicians·Ari VanderWalde, Arti Hurria
Jul 20, 2016·Menopause : the Journal of the North American Menopause Society·Carlo CervellatiVeronica Tisato
Oct 14, 2014·Journal of Obesity·Rafaela G FeresinReza Hakkak
Jul 17, 1998·Aging : Clinical and Experimental Research·R J ColmanJ W Kemnitz
Apr 7, 2007·The American Journal of Clinical Nutrition·Claudia S RiedtSue A Shapses
Aug 27, 2009·The Journal of Obstetrics and Gynaecology Research·Seung H LeeChan Y Park
Feb 15, 2007·The Journal of Clinical Endocrinology and Metabolism·Lan-Juan ZhaoHong-Wen Deng
Sep 23, 2011·Journal of Bone and Mineral Metabolism·Jarmo SaarelainenRisto Honkanen
Apr 13, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nobuhiro FukushimaMasayasu Kojima
Jun 20, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D ShinS M Park
May 30, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ibrahim Halil Sahin
Mar 26, 2014·Archives of Osteoporosis·Jennifer T LloydDenise L Orwig
Jan 16, 2018·Journal of Epidemiology·Dong-Won LeeJoohon Sung
Mar 25, 1998·Journal of Women's Health·S C Finn
Nov 7, 2002·Health Care for Women International·Karyn HolmJane Walker
Oct 27, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·N YoshimuraT Nakamura
Feb 5, 2011·Radiology·Margaret J HenryGeoffrey C Nicholson
Feb 27, 2014·Journal of Bone and Mineral Metabolism·Kyong-Chol KimJose M Ordovas
Aug 30, 2017·Public Health Nutrition·Yu-Hung HuangShyh-Hsiang Lin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.