Puzzle of hormone replacement therapy and prospect of the role of traditional Chinese medicine in treating postmenopausal syndrome

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Ming-Dao Chen, Ying Yang

Abstract

In July 2002, the Women's Heath Initiative (WHI) clinical trial, designed to clarify the risks and benefits of combination hormone replacement therapy (HRT) to the postmenopausal women declared that interim safety review after an average follow-up of 5.2 years found that a combination of estrogen and progestin frequently prescribed to postmenopausal women in USA increased the risk of invasive breast cancer, heart disease, stroke, and pulmonary embolism while reduced bone fractures and colorectal cancer. The overall risks of HRT outweigh the benefits, which provides an opportunity for traditional Chinese medicine (TCM) going abroad. A variety of clinical and experimental evidences have showed that TCM exerts quite satisfactory effect on relieving postmenopausal symptoms with little adverse effect, hence a potential role to replace or to improve HRT or to reduce the side effect induced by HRT.

References

Jul 2, 2002·JAMA : the Journal of the American Medical Association·Stephen HulleyUNKNOWN HERS Research Group
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
Jul 16, 2002·JAMA : the Journal of the American Medical Association·Suzanne W Fletcher, Graham A Colditz

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Citations

Sep 2, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Wen-Jian WangFeng Tang
Jan 1, 2009·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Jue Zhou, Fan Qu
Oct 2, 2007·Explore : the Journal of Science and Healing·Jue ZhouDaiyi Tang
Mar 8, 2007·Forschende Komplementärmedizin = Research in Complementary Medicine·Fan QuRui Nan

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