PVC flooring at home and uptake of phthalates in pregnant women

Indoor Air
Huan ShuCarl-Gustaf Bornehag

Abstract

Phthalates are used as plasticizers in polyvinyl chloride (PVC) materials and it is known that phthalates may migrate into the surrounding environment and then become a source for human uptake. The aim of the study was to investigate whether residential PVC flooring was related to the urinary levels of phthalate metabolites determined in pregnant women. The data were from the Swedish SELMA study where sampling was conducted during the time period 2007-2010. Spot urine samples from 1674 women at the end of the first trimester were analyzed for 14 metabolites from seven phthalates and one phthalate alternative. Data on flooring material in the kitchen and the parents' bedrooms as well as potential confounders were collected by postal questionnaires at the same time as the urine samples were taken. Multiple regression modeling by least square geometric mean and weighted quantile sum regression was applied to log-transformed and creatinine-adjusted phthalate metabolite concentrations adjusted for potential confounders from questionnaire data. This study has found significantly higher urinary levels of the BBzP metabolite (MBzP) in pregnant women living in homes with PVC flooring as compared to homes with other flooring materials.

References

Jan 1, 1973·Environmental Health Perspectives·P R Graham
May 11, 2002·Environmental Health Perspectives·Jane A HoppinDonna D Baird
Mar 11, 2004·Indoor Air·A AfshariV Hansen
Aug 5, 2005·Environmental Health Perspectives·Shanna H SwanUNKNOWN Study for Future Families Research Team
Oct 6, 2005·Environmental Health Perspectives·Carl-Gustaf BornehagJan Sundell
Feb 10, 2006·International Journal of Andrology·Ted Schettler
Apr 3, 2007·International Journal of Hygiene and Environmental Health·Matthias WittassekChristoph Schlüter
Feb 5, 2008·Pediatrics·Sheela SathyanarayanaShanna H Swan
Jul 22, 2008·Environment International·Po-Chin HuangChing-Chang Lee
Sep 15, 2009·Biological Psychiatry·Bung-Nyun KimYun-Chul Hong
Nov 19, 2009·International Journal of Andrology·S H SwanB Weiss
Jan 12, 2010·International Journal of Andrology·C G Bornehag, E Nanberg
Jan 29, 2010·Environmental Health Perspectives·Stephanie M EngelMary S Wolff
Mar 3, 2010·Environmental Health Perspectives·Soo-Churl ChoHyo-Won Kim
Apr 22, 2011·Bulletin of Environmental Contamination and Toxicology·M I González-CastroA De León-Rodríguez
Jun 24, 2011·International Journal of Andrology·Y SuzukiH Shiraishi
Mar 9, 2012·Environmental Health Perspectives·Morten Søndergaard JensenBo A G Jönsson
May 9, 2012·Indoor Air·F CarlstedtC-G Bornehag
Jul 5, 2012·Journal of Exposure Science & Environmental Epidemiology·Jessie P BuckleyJane A Hoppin
Aug 14, 2012·Paediatric and Perinatal Epidemiology·Carl-Gustaf BornehagStaffan Janson
Feb 23, 2013·Current Opinion in Pediatrics·Joseph M BraunRuss Hauser
Jul 1, 2014·Environmental Science & Technology·Deborah J WatkinsJoseph M Braun
Oct 30, 2014·Environmental Health Perspectives·Carl-Gustaf BornehagShanna H Swan
Feb 19, 2015·Journal of Exposure Science & Environmental Epidemiology·Allan C JustRobin M Whyatt
Feb 24, 2015·Human Reproduction·S H SwanUNKNOWN TIDES Study Team
Dec 17, 2015·Environmental Health Perspectives·Tina Kold JensenAnna-Maria Andersson
Feb 28, 2017·Environmental Science & Technology·Vilma SukieneKonrad Hungerbühler
Mar 1, 2015·Journal of Agricultural, Biological, and Environmental Statistics·Caroline CarricoPam Factor-Litvak

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Citations

Nov 2, 2019·Environmental Health : a Global Access Science Source·Yuri Levin-SchwartzRobert O Wright
Jul 28, 2019·Indoor Air·Emmanuelle CastagnoliHeidi Salonen
Jun 24, 2019·Environment International·Georgios GiovanoulisAnne Lagerqvist
Jul 1, 2021·Allergy and Asthma Proceedings·Minyoung JungYong Mean Park
Dec 16, 2020·Environmental Science & Technology·Clara M A EichlerJohn C Little

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