Pyoderma gangrenosum after breast surgery: A systematic review

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
Denis C EhrlP Niclas Broer

Abstract

Post-surgical pyoderma gangrenosum (PSPG) is a rare inflammatory skin disorder of unknown aetiology. Given its similar presentation to wound infection and lack of reliable diagnostic tests as well as pathognomonic clinical features, PSPG is difficult to diagnose. The aim of this review was to identify factors contributing to PSPG to aid with timely diagnosis and appropriate therapy. A systematic literature review was performed by following PRISMA guidelines, focusing on PSPG after reconstructive and aesthetic breast surgery. The online databases PubMed, Medline, EMBASE, Scopus, and Cochrane were used, and additionally, a Google© search was performed. A total of 68 articles describing 87 cases of PSPG following aesthetic and reconstructive breast surgery were found. The majority of PSPG (44%) occurred after breast reduction surgery and microsurgical breast reconstruction (16%). The most common associated conditions were malignancies in 37% and autoimmune deficiencies in 17%. Microbiological examinations were found to have a negative result in 90%. The median time from initial presentation with symptoms to correct diagnosis of PG was on average 12.5 days, with unsuccessful first-line therapy on average for 20.0 days. After the di...Continue Reading

Citations

Jun 24, 2019·ANZ Journal of Surgery·Edgardo SolisElisabeth Elder
Aug 17, 2019·International Wound Journal·Cenk DemirdoverHaluk Vayvada
Jan 9, 2020·Diagnosis·Ashley M ReeseAlex G Ortega-Loayza
Sep 13, 2019·Annals of Plastic Surgery·Juan Rodolfo MellaLifei Guo
Jul 28, 2020·The Breast Journal·Laura M Cabañas WeiszJuan José García Gutiérrez
Nov 24, 2020·International Journal of Dermatology·Emily C MilamMiriam K Pomeranz
Sep 20, 2018·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Lucia BrambillaEmilio Berti
Dec 17, 2020·Curēus·Jesus Zapata Alvarez, Alfredo Patrón Gómez
May 25, 2021·The Breast Journal·Matthew D RichWarren Schubert
Jun 16, 2021·Journal of breast cancer·Dabin KimZisun Kim
Aug 9, 2021·ANZ Journal of Surgery·James BriffaGary Kode

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