Pyogenic arthritis of native joints in non-intravenous drug users: A detailed analysis of 268 cases attended in a tertiary hospital over a 22-year period

Seminars in Arthritis and Rheumatism
Joan M NollaJavier Ariza

Abstract

To analyze the clinical features, microbiological spectrum, diagnostic procedures and outcomes in native joint pyogenic arthritis among non-intravenous drug users. We collected all microbiologically proved cases of infectious arthritis at our hospital between 1992 and 2013. Patients with prosthetic joint infection were excluded, as were patients with non-pyogenic arthritis and intravenous drug users. We identified 268 patients; the mean age was 61 ± 14.7 years and 62% were men. The incidence increased over the period of study. In 188 patients (70%), one or more underlying medical illnesses were found. The mean symptom duration was 8.9 ± 9.5 days. Globally, 311 affected joints were found, 232 (75%) involving peripheral joints and 79 (25%) axial joints. Staphylococci (55%) and Streptococci (29%) were the predominant microorganisms. Blood cultures were positive in 78% (173/223) of the cases. In 81 patients (30%), one or more concomitant infectious processes were found. Antimicrobial therapy was prescribed 4-8 weeks in most cases, and surgical drainage was performed in 65% of patients. Four patients relapsed and 23 (8%) died. The prevalence of pyogenic native joint arthritis in non-intravenous drug users is increasing, frequently a...Continue Reading

References

Oct 1, 1991·Seminars in Arthritis and Rheumatism·M A BrancósJ Muñoz-Gomez
Aug 1, 1993·Annals of the Rheumatic Diseases·S Muñoz-FernándezJ Gijón Baños
Aug 1, 1997·Annals of the Rheumatic Diseases·C J KaandorpB A Dijkmans
Feb 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·F FleischC Ruef
Sep 20, 2001·International Orthopaedics·D C WirtzK W Zilkens
Oct 5, 2002·Clinical Microbiology Reviews·Mark E Shirtliff, Jon T Mader
Oct 16, 2004·The New England Journal of Medicine·Werner ZimmerliPeter E Ochsner
Apr 18, 2006·Seminars in Arthritis and Rheumatism·Javier NarváezJavier Ariza
Jul 11, 2006·Rheumatology·G CoakleyUNKNOWN British Society for Rheumatology Standards, Guidelines and Audit Working Group
Jun 3, 2009·The Journal of Bone and Joint Surgery. American Volume·Douglas M Sammer, Alexander Y Shin
Mar 9, 2010·Lancet·Catherine J MathewsGerald Coakley
Mar 12, 2011·The Journal of Antimicrobial Chemotherapy·Olivier ClercLaurence Senn
Nov 1, 2011·Seminars in Arthritis and Rheumatism·Monthida Fangtham, Alan N Baer
Nov 22, 2011·Best Practice & Research. Clinical Rheumatology·Miriam García-AriasEmilio Martín Mola
Jan 31, 2012·Infectious Disease Clinics of North America·Emily K ShumanPreeti N Malani
Jul 4, 2012·Journal of Shoulder and Elbow Surgery·Matthew P AbdelJoseph R Cass
Oct 10, 2012·Current Opinion in Microbiology·José R MediavillaBarry N Kreiswirth
Nov 28, 2012·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ilker UçkayDaniel Lew
May 14, 2014·The Journal of Venomous Animals and Toxins Including Tropical Diseases·Priscila Maria Colavite, Alexandrina Sartori
Jun 25, 2014·Joint, Bone, Spine : Revue Du Rhumatisme·Jean-Jacques DubostMartin Soubrier
Aug 12, 2014·Journal of Orthopaedics·María-Carmen Muñoz-EgeaJaime Esteban

❮ Previous
Next ❯

Citations

Aug 29, 2016·Reumatología clinica·María Guerrero VadilloMaría Francisca Portero Azorín
Dec 8, 2017·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Bryan Josué Flores-RoblesJuan Mulero Mendoza
May 23, 2020·Rheumatology·Yi-Ching HuangChih-Chiang Chien
Jan 17, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Valeria FabreSara E Cosgrove
Dec 13, 2016·Clinical Orthopaedics and Related Research·Jason M JenningsDavid C McNabb
Aug 8, 2020·Joint, Bone, Spine : Revue Du Rhumatisme·Marion CoudercUNKNOWN French Rheumatology Society Bone, Joint Infection Working Group
Sep 19, 2021·Annals of the Rheumatic Diseases·Signý Lea GunnlaugsdóttirMagnús Gottfreðsson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Cellulitis

Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.