Pyogenic granuloma: an unrecognized cause of gastrointestinal bleeding

Virchows Archiv : an International Journal of Pathology
Susanne van EedenCarel J M van Noesel

Abstract

Pyogenic granuloma is a lobular capillary hemangioma that mostly occurs on the skin, but it is also encountered on the mucosal surface of the oral cavity. Only a few cases in other parts of the digestive tract have been reported in Japanese patients. In this report, two Caucasian patients are described, who presented with gastrointestinal bleeding due to the presence of a pyogenic granuloma. One was located in the distal esophagus and could be treated with local excision and laser-photocoagulation therapy. The other one was located in the small intestine and was removed by surgical resection. Although extremely rare, pyogenic granuloma as a cause of gastrointestinal bleeding needs consideration. The lesion is benign, presumably reactive and can be adequately treated by excision or laser photocoagulation. Immunohistochemistry and/or polymerase chain reaction for herpesvirus 8 can reliably distinguish pyogenic granuloma from Kaposi's sarcoma, an important differential diagnosis.

Citations

Feb 22, 2012·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Elife ErarslanOsman Yüksel
Jan 1, 2009·BMJ Case Reports·Silvia TaccognaZaccaria Rossi
Jan 23, 2014·Gastroenterología y hepatología·Juan Egea ValenzuelaFernando Alberca de las Parras
Sep 17, 2014·Internal Medicine·Azusa KikuchiHiroyuki Imaeda
Sep 23, 2014·Abdominal Imaging·David W BrandelAshish P Wasnik
Jul 18, 2015·Clinical Journal of Gastroenterology·Kenro HirataTakanori Kanai
Jul 17, 2015·Internal Medicine·Masaya IwamuroKazuhide Yamamoto
Apr 25, 2007·Gastrointestinal Endoscopy·Elisabeth R HoekstraPieter Scholten
Oct 9, 2015·BMC Gastroenterology·Shun-Ichi MisawaHiroyoshi Ota
Aug 8, 2015·Clinical Nuclear Medicine·Amir IravaniSusan Sparrow
Sep 15, 2012·Journal of Pediatric Surgery·Shannon L CastleDonald B Shaul
May 11, 2016·Revista de gastroenterología de México·J De MaríaR Matanó
Jul 13, 2016·Case Reports in Gastrointestinal Medicine·Marshall W MeeksJin-Ping Lai
May 9, 2018·International Journal of Surgical Pathology·David A Suarez-ZamoraMauricio A Palau-Lazaro
Oct 31, 2019·Case Reports in Gastrointestinal Medicine·Elias EstifanMatthew Grossman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Pediatric Gastroenterology and Nutrition
Samra Sarigol BlanchardJudy Splawski
Gastrointestinal Endoscopy
Katsuro ShirakawaAkira Terano
Annals of Diagnostic Pathology
Maria Carmen González-VelaCovadonga García-Suárez
The American Journal of Dermatopathology
Jean L UrquhartSabine Kohler
© 2022 Meta ULC. All rights reserved