Pyogenic liver abscess in ESRD patients undergoing maintenance dialysis therapy

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Ya-Fei YangChiu-Ching Huang

Abstract

Patients with end-stage renal disease (ESRD) on dialysis therapy have increased susceptibility to bacterial infection. Data regarding pyogenic liver abscess in this population are rare. We retrospectively examined all cases of pyogenic liver abscess in patients undergoing maintenance dialysis therapy in 2 tertiary referral centers. Medical records of patients with ESRD with a pyogenic liver abscess from January 1995 to September 2004 were studied. Twenty-seven of 20,676 admitted patients with ESRD were found to have a pyogenic liver abscess. The major predisposing factor was diabetes mellitus (59.3%). The most common clinical symptoms were fever and chills (85.2%). A rare presentation of hiccup was noted in 2 peritoneal dialysis patients, and endophthalmitis was noted in 2 patients with liver abscess caused by Klebsiella pneumoniae. Abscesses were located mainly in the right lobe (70.4%) and presented as a solitary mass (74.1%). K pneumoniae was the most common bacteria isolated in blood cultures (51.9%) and liver abscess aspirates (37%). Invasive drainage approaches performed in 17 patients (63%) resulted in a unique complication of peritonitis in 4 peritoneal dialysis patients. The difference in mortality rates between patien...Continue Reading

References

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Citations

Oct 2, 2008·Emerging Infectious Diseases·Feng-Chiao TsaiJin-Town Wang
Dec 27, 2011·Journal of the Chinese Medical Association : JCMA·Shih-Chao Kang, Shinn-Jang Hwang
Jun 21, 2014·Hemodialysis International·Lung-Wen TsaiChien-Tsai Liu

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