Pyrethroid insecticide-resistant strain of Aedes aegypti from Cuba induced by deltamethrin selection

Journal of the American Mosquito Control Association
María M RodríguezFrancisco Ramos

Abstract

A sample of Aedes aegypti L. from Santiago de Cuba with a high level of deltamethrin resistance (113.7 x at the 50% lethal concentration [LC50]), was subjected to deltamethrin selection to determine the capacity of this population to evolve higher resistance under intensive laboratory selection pressure, to characterize that resistance, to attempt to identify some of the mechanisms involved, and to use it as a reference strain for future molecular research. High resistance developed after 12 generations of selection (1,425 x). After selection for 12 generations with deltamethrin, the Santiago de Cuba colony (SAN-F12) showed little or no cross-resistance to the organophosphates evaluated, but high cross-resistance was observed for all the pyrethroids in larvae from this strain: lambdacyhalothrin (197.5 x), cypermethrin (45 x), and cyfluthrin (41.2 x). Adult bioassays reveal that a SAN-F12 strain was resistant to the pyrethroid and the organochlorine dichlorodiphenyltrichloroethane (DDT). Synergism tests implicated detoxifying esterase or glutathione S-transferase (GST) and monooxygenase in pyrethroid resistance. Biochemical tests reveal that acetylcholinesterase was not involved in deltamethrin resistance. The frequency of GST e...Continue Reading

References

Jan 1, 1991·Toxicon : Official Journal of the International Society on Toxinology·J S Kirchberg, T M Davidson
Apr 1, 1997·The American Journal of Tropical Medicine and Hygiene·Y B MebrahtuM Taylor
Feb 18, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J B BergéM Amichot
Feb 27, 2001·Insect Biochemistry and Molecular Biology·I KostaropoulosE Papadopoulou-Mourkidou
Jun 1, 1961·The Biochemical Journal·J BoothP Sims

❮ Previous
Next ❯

Citations

May 18, 2011·Parasites & Vectors·Basile KamgangChristophe Paupy
Jan 29, 2011·Bulletin of Entomological Research·K A PolsonD D Chadee
Jan 9, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jean-Philippe DavidMark John Ingraham Paine
Jun 6, 2009·Journal of Medical Entomology·Julia W PridgeonKenneth J Linthicum
Aug 27, 2015·Acta Tropica·Hélio Daniel Ribeiro RochaMaria Alice Varjal de Melo Santos
Oct 29, 2011·Insect Molecular Biology·K Saavedra-RodriguezWilliam C Black
Mar 27, 2013·Tropical Medicine & International Health : TM & IH·R BoyceO Horstick
Jul 21, 2011·Asian Pacific Journal of Tropical Medicine·Sarita KumarMkk Pillai
Apr 7, 2015·Journal of the American Mosquito Control Association·Juan Andrés BissetIlario Fuentes
Jun 8, 2017·Journal of the American Mosquito Control Association·María Magdalena RodríguezJuan Andrés Bisset
Mar 15, 2018·Memórias do Instituto Oswaldo Cruz·Yanouk EpelboinIsabelle Dusfour
Aug 4, 2009·Journal of Medical Entomology·Julia W PridgeonKenneth J Linthicum
Sep 19, 2020·Pest Management Science·Dariane SouzaNicholas J Miller
Feb 15, 2012·Journal of the American Mosquito Control Association·Quetzaly SillerAdriana E Flores
Mar 9, 2017·Omics : a Journal of Integrative Biology·Rakhi DhawanAshwani Kumar
Feb 5, 2008·Journal of the American Mosquito Control Association·María M RodríguezDitter Fernández
Aug 12, 2020·Parasites & Vectors·H Sachini D FernandoB G D Nissanka Kolitha De Silva
Jan 14, 2011·Parasites & Vectors·Estelita Pereira LimaMaria Alice V de Melo Santos

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.