Apr 1, 1976

Pyridine nucleotide metabolism in imaginal discs of Drosophila melanogaster

Biochemical Genetics
T W KeyesE W Hanly

Abstract

The pyridine nucleotide metabolism of imaginal discs of Drosophila melanogaster has been studied in vitro by incubating discs with labeled nicotinic acid in the presence and absence of ecdysterone. The major labeled compounds found within the discs are NAD, NADP, and nicotinic acid. There is preferential uptake of nicotinamide over nicotinic acid, although the Priess-Handler pathway is used exclusively. The presence of ecdysterone produces a small increase in the NADP/NAD ratio, and an increase in NAD synthesis, probably to compensate for increased NAD turnover.

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Citations

Mentioned in this Paper

Biochemical Pathway
Nicotinamide Assay
Uptake
NADH
NADP
Biochemical Turnover
Niacin
Drosophila melanogaster
Tadpole
Ecdysterone

About this Paper

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