Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates

Angewandte Chemie
Ian R HazeldenJohn F Bower

Abstract

Ligand-enabled aza-Heck cyclizations and cascades of N-(pentafluorobenzoyloxy)carbamates are described. These studies encompass the first examples of efficient non-biased 6-exo aza-Heck cyclizations. The methodology provides direct and flexible access to carbamate protected pyrrolidines and piperidines.

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Citations

Jul 17, 2019·Angewandte Chemie·Feiyang XuDonald A Watson
Oct 2, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marek ČubiňákTomáš Tobrman
May 5, 2021·Angewandte Chemie·Lauren G O'Neil, John F Bower
Feb 19, 2019·Journal of the American Chemical Society·Xiaofeng MaJohn F Bower
Jun 12, 2019·Chemical Reviews·Katerina M Korch, Donald A Watson
Mar 18, 2020·Journal of the American Chemical Society·Liangxin FanXinjun Luan
Aug 31, 2021·Organic Letters·Katerina M Korch, Donald A Watson
Oct 7, 2021·Chemistry : a European Journal·Finn J GeffersDaniel B Werz

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