Pyrrolizidine alkaloids and beehive products: A review.

Food Chemistry
Patricia BrugnerottoAna Carolina Oliveira Costa

Abstract

Pyrrolizidine alkaloids (PA) are secondary metabolites of plants, which are mostly found in the genus Senecio, Echium, Crotalaria, and Eupatorium. The presence of 1,2-unsaturated PA in foods is a concern to food regulators around the world because these compounds have been associated to acute and chronic toxicity, mainly in the liver. The intake foods with PA/PANO usually occur through accidental ingestion of plants and their derivatives, besides to products of vegetal-animal origin, such as honey. PA/PANO are transferred to honey by their presence in nectar, honeydew, and pollen, which are collected from the flora by bees. In addition to honey, other beekeeping products, such as pollen, royal jelly, propolis, and beeswax, are also vulnerable to PA contamination. In this context, this review provides information about chemical characteristics, regulation, and toxicity, as well as summarizes and critically discusses scientific publications that evaluated PA in honeys, pollens, royal jelly, and propolis.

References

May 2, 2002·Journal of Agricultural and Food Chemistry·John A EdgarRussell J Molyneux
Feb 3, 2005·Journal of Agricultural and Food Chemistry·Michael BoppréJohn A Edgar
Feb 7, 2008·Annual Review of Plant Biology·Jörg Ziegler, Peter J Facchini
Jun 17, 2008·Journal of Agricultural and Food Chemistry·Michael BoppréOttmar W Fischer
Sep 25, 2009·Journal of Chemical Ecology·Annika ReinhardTill Beuerle
Dec 17, 2009·Molecular Nutrition & Food Research·Michael KempfTill Beuerle
Dec 17, 2009·Molecular Nutrition & Food Research·Michael KempfTill Beuerle
Mar 2, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·A DübeckeC Lüllmann
Dec 12, 2013·Analytical and Bioanalytical Chemistry·Michalina OplatowskaKatrina Campbell
May 20, 2014·Chemical Research in Toxicology·Jianqing RuanGe Lin
Sep 16, 2014·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Dorina BodiAnja These
Apr 11, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Guilherme Rabelo CoelhoGiuseppina Negri
Jun 24, 2015·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Claudia LuckertAlfonso Lampen
Oct 11, 2015·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·D HenatschR J Stokroos
Nov 13, 2015·International Journal of Molecular Sciences·Dominik SkonecznyLeslie A Weston
Jan 10, 2016·European Journal of Clinical Pharmacology·Victoria RollasonMonica Escher
Jun 1, 2016·Journal of Agricultural and Food Chemistry·Matteo A LucchettiChristina Kast
Dec 6, 2016·Toxins·Bryan L StegelmeierAmmon W Brown
Sep 26, 2017·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Patrick P J MulderAnja These
Sep 29, 2017·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Christina KastOtmar Zoller
Nov 22, 2017·Progress in Nuclear Magnetic Resonance Spectroscopy·Catherine DebordePatrick Giraudeau
Feb 28, 2018·Journal of Agricultural and Food Chemistry·Stephen W C Chung, Chi-Ho Lam
Mar 11, 2018·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Birgit DusemundAlfonso Lampen
May 2, 2018·Journal of Agricultural and Food Chemistry·Florian KaltnerChristoph Gottschalk
May 18, 2018·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Chuanhui MaTao Yi
Jun 8, 2018·International Journal of Molecular Sciences·Rute MoreiraPaula B Andrade
Jul 28, 2018·Phytochemistry·Vassya BankovaBoryana Trusheva
Aug 21, 2018·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ashley AllemangStefan Pfuhler
Oct 10, 2018·Trends in Plant Science·Chuanying FangJie Luo
Oct 27, 2018·Journal of Veterinary Research·Ewelina Kowalczyk, Krzysztof Kwiatek
Nov 23, 2018·Chemico-biological Interactions·Johanna EbmeyerStefanie Hessel-Pras
Apr 3, 2019·Complementary Therapies in Medicine·Vahid MalekiMohammad Alizadeh
May 20, 2019·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Johanna EbmeyerAlfonso Lampen
May 31, 2019·Journal of Agricultural and Food Chemistry·Matheus Carpinelli de JesusMary T Fletcher
Jun 16, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Christina KastOtmar Zoller

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Citations

Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Anjaramampionona Henintsoa Duvale SolofomalalaAhcène Boumendjel
Jul 16, 2021·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Andressa Camargo ValeseAna Carolina Oliveira Costa

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