PMID: 376870Mar 1, 1979Paper

Q beta-defective particles produced in a streptomycin-resistant Escherichia coli mutant

Journal of Virology
H Engelberg-KulkaA Friedmann

Abstract

This paper describes Q beta noninfectious particles produced at 41 degrees C in a streptomycin-resistant Escherichia coli mutant which is temperature sensitive for suppression of a nonsense codon. The noninfectious particles resembled Q beta under the electron microscope and contained coat protein molecules in an amount similar to the amount in Q beta. However, they did not adsorb to F-piliated bacteria, and they were deficient in both minor capsid proteins of Q beta, maturation (IIa) and read-through (IIb). Proteins IIa and IIb were not produced in Qbeta-infected mutant cells at 41 degrees C. In addition, instead of the 30S RNA of Q beta, a shorter RNA, which sedimented mainly at 23 S, was found in the defective particles. The results are discussed in relation to the roles of proteins IIa and IIb of Q beta.

References

Feb 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J L YatesM Nomura
Mar 5, 1976·Journal of Molecular Biology·H J Vollenweider, T Koller
Jan 2, 1976·European Journal of Biochemistry·H G Wittmann
May 14, 1968·Journal of Molecular Biology·J A Steitz
Dec 6, 1974·Biochimica Et Biophysica Acta·H HofstetterC Weissmann
Mar 1, 1968·The Journal of Antibiotics·H UmezawaK Nitta
Jul 22, 1969·Biochimica Et Biophysica Acta·D GarwesS Ochoa
Feb 14, 1970·Journal of Molecular Biology·P Strigini, L Gorini
Oct 1, 1970·Virology·H JockuschP Kaesberg
Feb 28, 1971·Journal of Molecular Biology·T S ChanN D Zinder
Dec 1, 1968·Japanese Journal of Microbiology·T SakuraiI Watanabe
Nov 15, 1968·Experientia·G C Lancini, G Sartori
Aug 1, 1971·Virology·K HoriuchiS Matsuhashi
May 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·G FeixC Weissmann
Oct 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·J W Roberts, J E Steitz
Sep 15, 1971·Nature: New Biology·C H MooreC Weissmann
Sep 15, 1971·Nature: New Biology·A M Weiner, K Weber
Sep 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·T MiyakeK Yamane
Jan 1, 1966·Annual Review of Microbiology·L Gorini, J R Beckwith
Jun 15, 1964·Biochemical and Biophysical Research Communications·M CouturierR Thomas
Jul 18, 1970·Nature·W KonigsbergK Weber
May 14, 1968·Journal of Molecular Biology·J A Steitz
Dec 1, 1966·Journal of Bacteriology·C VasquezR M Franklin
Apr 1, 1964·Journal of Molecular Biology·R F GESTELAND, H BOEDTKER
Jan 1, 1965·Journal of Molecular Biology·N K SINHAP KAESBERG
Nov 28, 1966·Journal of Molecular Biology·J E Argetsinger, G N Gussin

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Citations

Jan 1, 1982·Molecular & General Genetics : MGG·A JoshiM Chakravorty
Feb 26, 1979·Molecular & General Genetics : MGG·H Engelberg-KulkaM Belfort
Feb 1, 1986·Archives of Microbiology·D I AnderssonC G Kurland
Jan 1, 1982·Molecular & General Genetics : MGG·H Engelberg-KulkaR Schoulaker-Schwarz
Jun 1, 1981·Journal of Virology·R Schoulaker-Schwarz, H Engelberg-Kulka
Feb 27, 1981·Biochemical and Biophysical Research Communications·H Engelberg-KulkaM Israeli-Reches
Apr 21, 1988·Journal of Theoretical Biology·H Engelberg-Kulka, R Schoulaker-Schwarz

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