Qat Chewing and Periodontal Pathogens in Health and Disease: Further Evidence for a Prebiotic-Like Effect

BioMed Research International
A Al-AlimiNezar N Al-Hebshi

Abstract

Qat chewing has been reported to induce subgingival microbial shifts suggestive of prebiotic-like properties. The objective here was to assess the effect of qat chewing on a panel of classical and new putative periopathogens in health and periodontitis. 40 qat chewers and 40 nonchewers, equally stratified by periodontal health status, were recruited. Taqman, real-time PCR was used to quantify total bacteria, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Parvimonas micra, Filifactor alocis, Synergistetes, and TM7s in pooled subgingival biofilm samples. Differences in microbial parameters between the study groups were analysed using ordinal regression. In health, the qat chewers harboured significantly lower relative counts of P. gingivalis, T. forsythia, Synergistetes, and TM7s after adjustment for multiple comparisons (P ≤ 0.007). At nominal significance level, they also carried lower counts of TM7s and P. micra (P ≤ 0.05). In periodontitis, the chewers had lower counts of all taxa; however, only T. denticola withstood correction for multiple comparisons (P ≤ 0.0063). Qat chewing is associated with lower proportions of periopathogens, particularly in subjects with healthy periodontium, which supports prev...Continue Reading

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Citations

Jul 3, 2018·International Journal of Dental Hygiene·A Al-AlimiN N Al-Hebshi
Jul 13, 2018·Journal of Clinical Periodontology·Yara L A S LeviLuciana P Maia
Aug 24, 2017·Journal of Investigative and Clinical Dentistry·Sadeq A Al-MaweriAbdulaziz Samran

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Methods Mentioned

BETA
PCR

Software Mentioned

PrimerDesign
SPSS

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