QseC Mediates Osmotic Stress Resistance and Biofilm Formation in Haemophilus parasuis

Frontiers in Microbiology
Lvqin HeYiping Wen

Abstract

Haemophilus parasuis is known as a commensal organism discovered in the upper respiratory tract of swine where the pathogenic bacteria survive in various adverse environmental stress. QseC, a histidine protein kinase of the two-component regulatory systems CheY/QseC, is involved in the environmental adaptation in bacteria. To investigate the role of QseC in coping with the adverse environment stresses and survive in the host, we constructed a qseC mutant of H. parasuis serovar 13 strain (ΔqseC), MY1902. In this study, we found that QseC was involved in stress tolerance of H. parasuis, by the ΔqseC exhibited a decreased resistance to osmotic pressure, oxidative stress, and heat shock. Moreover, the ΔqseC weakened the ability to take up iron and biofilm formation. We also found that the QseC participate in sensing the epinephrine in environment to regulate the density of H. parasuis.

References

Aug 31, 2000·Annual Review of Biochemistry·A M StockP N Goudreau
Jul 9, 2003·Proceedings of the National Academy of Sciences of the United States of America·Vanessa SperandioJames B Kaper
Sep 11, 2003·Journal of Neuroimmunology·Benedict T GreenDavid R Brown
Jan 27, 2004·Infection and Immunity·Amanda J BeddekPaul R Langford
Mar 17, 2004·Veterinary Microbiology·Simone Oliveira, Carlos Pijoan
Feb 15, 2005·Veterinary Microbiology·Anna BigasMontserrat Llagostera
May 27, 2005·Veterinary Microbiology·Jeffrey B Kaplan, Martha H Mulks
Nov 8, 2005·Veterinary Microbiology·Xuwang CaiMeilin Jin
Feb 21, 2006·International Journal of Medical Microbiology : IJMM·Matthew Walters, Vanessa Sperandio
Jun 29, 2006·Proceedings of the National Academy of Sciences of the United States of America·Marcie B ClarkeVanessa Sperandio
Jun 5, 2007·Molecular Microbiology·Sandy M S WongBrian J Akerley
Nov 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Yoko EguchiRyutaro Utsumi
Aug 22, 2009·PLoS Pathogens·David T HughesVanessa Sperandio
Feb 6, 2010·Current Opinion in Microbiology·Kristin WuichetIgor B Zhulin
Sep 2, 2010·Infection and Immunity·Maria Labandeira-ReyEric J Hansen
May 6, 2011·Molecular Microbiology·Maria HadjifrangiskouScott J Hultgren
Sep 8, 2012·International Journal of Medical Microbiology : IJMM·Can M UnalKristian Riesbeck
Nov 13, 2012·Biotechnology Advances·Vipin Chandra Kalia
Jun 15, 2014·International Journal of Medical Microbiology : IJMM·Gheyath K NasrallahRafael A Garduño

❮ Previous
Next ❯

Citations

Aug 17, 2020·Veterinary Research·Shulin FuChien-An Andy Hu
Mar 12, 2020·Frontiers in Cellular and Infection Microbiology·Changsheng JiangQigai He
Nov 1, 2020·International Journal of Molecular Sciences·Yves Combarnous, Thi Mong Diep Nguyen
May 1, 2021·Microorganisms·Sergey Vladislavovich Mart'yanovAndrei Vladislavovich Gannesen
May 14, 2021·Veterinary Microbiology·Ruijiao JiangYin Wang

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
reverse transcription PCR

Related Concepts

Related Feeds

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

© 2022 Meta ULC. All rights reserved