QT dispersion increases with aging.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Bunyamin YavuzAli Oto

Abstract

Age-related changes in cardiovascular system are well-known. Arrhythmias in elderly patients constitute most of the urgencies, consultations, or hospitalizations. QT dispersion (QTd) is a simple noninvasive arrhythmogenic marker to demonstrate the electrical instability of the heart. The aim of this study was to investigate how QTd changes with increasing age by calculating the QTd in the elderly and younger subjects. One hundred and forty-six consecutive subjects (62 males and 84 females; age range: 18-82 years) were enrolled in the study. Sixty-seven of the subjects were 65 years and over (mean age, 70 +/- 4), 79 were younger than 65 (mean age, 37 +/- 11). A 12-lead ECG was recorded. The longest and the shortest QT intervals were measured manually on these ECG recordings. QTd was calculated from the formula, QTd = QTmax - QTmin. Demographic features were similar between the two groups. QTd of the elderly group was found to be significantly higher than the younger group (35.6 +/- 15.6 in elderly, 24.2 +/- 12.4 in younger group, P < 0.001). A positive relationship was found between QTd and age (r = 0.415, P < 0.001). QTd was greater in female than in male (31.9 +/- 16.7 ms vs 26.0 +/- 11.3 ms, respectively, P = 0.018). Our stud...Continue Reading

References

Jul 1, 1992·Disease-a-month : DM·R M Cherniack
Jun 1, 1990·British Heart Journal·C P DayR W Campbell
Aug 1, 1989·Cardiovascular Research·M EghbaliO O Blumenfeld
Oct 1, 1971·Circulation Research·B GribbinR Peto
Apr 15, 1995·Lancet·J M GlancyD P de Bono
Mar 1, 1995·Journal of the American College of Cardiology·M ZabelM R Franz
Nov 14, 1997·Pacing and Clinical Electrophysiology : PACE·M ZabelM R Franz
Nov 14, 1997·Pacing and Clinical Electrophysiology : PACE·J Kautzner, M Malik
Apr 18, 2000·Progress in Cardiovascular Diseases·M R Franz, M Zabel
Apr 25, 2000·American Journal of Hypertension·J TankM Weck
Feb 13, 2001·The American Journal of Cardiology·S SabaN A Estes
May 3, 2001·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·H TranJ Kluger
Nov 13, 2001·Current Opinion in Cardiology·J VaragicE Frohlich
May 27, 2003·Cardiac Electrophysiology Review·Béatrice Brembilla-Perrot

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Citations

Dec 1, 2010·Scandinavian Cardiovascular Journal : SCJ·Igor PshenichnikovJüri Kaik
Apr 28, 2007·Clinics in Geriatric Medicine·Bryan D HayesFermin Barrueto
Jul 31, 2010·Journal of Cardiovascular Medicine·Ahmet A YalcinEmre Tutal
Dec 27, 2016·Clinical and Experimental Pharmacology & Physiology·Kamalan JeevaratnamChristopher L-H Huang

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