PMID: 3753410Jan 1, 1986Paper

Qualitative and quantitative assessment of human polymorphonuclear leukocyte (PMNL) functions

Beiträge Zu Infusionstherapie Und Klinische Ernährung
M SchmittH Cottier

Abstract

The current status on human PMNL separation, storage conditions, and quantitative assessment of cell functions is discussed. Human peripheral blood PMNLs are multifunctional cells which may be activated by several soluble and particulate stimuli. A variety of methods for the isolation of PMNLs and testing of cell functions is described which may be used in the clinical and the research laboratory. Detailed information on the quantitative assessment of PMNL motility, phagocytosis, microbial killing, exocytosis, and oxygen metabolite generation is given. Recently developed biochemical and immunological methods which may be employed for detection of structural and metabolic changes in normal and pathological PMNLs are also included.

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.