Qualitative "trial-sibling" studies and "unrelated" qualitative studies contributed to complex intervention reviews

Journal of Clinical Epidemiology
Jane NoyesArash Rashidian

Abstract

To compare the contribution of "trial-sibling" and "unrelated" qualitative studies in complex intervention reviews. Researchers are using qualitative "trial-sibling" studies undertaken alongside trials to provide explanations to understand complex interventions. In the absence of qualitative "trial-sibling" studies, it is not known if qualitative studies "unrelated" to trials are helpful. Trials, "trial-sibling," and "unrelated" qualitative studies looking at three health system interventions were identified. We looked for similarities and differences between the two types of qualitative studies, such as participants, intervention delivery, context, study quality and reporting, and contribution to understanding trial results. Reporting was generally poor in both qualitative study types. We detected no substantial differences in participant characteristics. Interventions in qualitative "trial-sibling" studies were delivered using standardized protocols, whereas interventions in "unrelated" qualitative studies were delivered in routine care. Qualitative "trial-sibling" studies alone provided insufficient data to develop meaningful transferrable explanations beyond the trial context, and their limited focus on immediate implementa...Continue Reading

References

Oct 3, 1999·Journal of the American Academy of Nurse Practitioners·G Birkholz, D C Viens
Sep 19, 2001·Health & Social Care in the Community·Angela V. TaggartLesley Barclay
Apr 25, 2002·British Journal of Community Nursing·E R Perkins, J MacFarlane
Jan 7, 2003·British Journal of Nursing : BJN·Jenny DrewDavid Hall
Feb 8, 2003·British Journal of Nursing : BJN·Jenny DrewDavid Hall
Dec 4, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Iftekhar QuasemA M R Chowdhury
Mar 23, 2004·Contraception·Annika A G VosToine L M Lagro-Janssen
Jun 18, 2004·Journal of Health & Social Policy·Vanessa B SheppardJoann T Richardson
Sep 15, 2004·Lancet·Dharma S ManandharUNKNOWN Members of the MIRA Makwanpur trial team
Feb 26, 2005·Contemporary Nurse·Jill DownieKaty Clemenston
Mar 18, 2005·BMC Pregnancy and Childbirth·Joanna MorrisonAnthony Costello
Mar 16, 2007·MCN. the American Journal of Maternal Child Nursing·Roberta WoodgateJudy Brown
Jul 25, 2007·Journal of Pediatric Nursing·Maureen HeamanJudy Brown
Sep 18, 2007·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Allison TongJonathan Craig
Jul 16, 2008·Annals of Family Medicine·Carolyn A Chew-GrahamSarah Peters
Dec 24, 2008·MCN. the American Journal of Maternal Child Nursing·Troy CarltonDena Walker
Feb 5, 2009·Journal of Advanced Nursing·Angelique T M Dierick-van DaeleHubertus J M Vrijhoef
Jul 1, 2009·Pediatrics·Tumaini R CokerMichael A Rodriguez
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Sep 2, 2009·Child: Care, Health and Development·J BarnesK MacPherson
Dec 31, 2009·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Helene R Voogdt-PruisJan W Van Ree
Apr 27, 2010·BMJ : British Medical Journal·Alison J WeardenUNKNOWN Fatigue Intervention by Nurses Evaluation (FINE) trial writing group and the FINE trial group
Jun 5, 2010·Archives of Disease in Childhood·M E CupplesH L Halliday
Jul 14, 2010·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Kenneth F SchulzUNKNOWN Consort Group
Aug 21, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·M CourtenayN Carey
Oct 28, 2010·International Breastfeeding Journal·Jolly NankundaUNKNOWN PROMISE-EBF Study Group
Jan 5, 2011·Journal of Clinical Epidemiology·Gordon GuyattHolger J Schünemann
Apr 5, 2011·Primary Health Care Research & Development·Carolyn Chew-GrahamSarah Peters
Aug 21, 2013·Journal of Clinical Epidemiology·Laurie M AndersonIan Shemilt
Mar 21, 2015·BMJ : British Medical Journal·Graham F MooreJanis Baird

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