Quality and Brands of Amoxicillin Formulations in Nairobi, Kenya.

BioMed Research International
Lilian C KoechLucia K Keter

Abstract

Antibiotics are among the most counterfeited anti-infectious medicines in developing countries. Amoxicillin is one of the commonly prescribed, affordable, and easily accessible antibiotic in Kenya. It is a broad-spectrum antibiotic hence commonly used in chemotherapy. This study sought to determine the quality and identify the various brands of amoxicillin and its combination amoxicillin/clavulanic acid marketed in Nairobi County. Nairobi is the capital city of Kenya, gateway for imports and exports, and the headquarters to most of the pharmaceutical distributors. Ten wards in Nairobi County representing different socioeconomic settings were purposively sampled for the study. A detailed questionnaire was used to collect background data on brands of amoxicillin and amoxicillin/clavulanic acid in the market. A total of 106 different brands were found in the market: 85 were imports while 21 were locally manufactured. Fifty-three samples were analyzed with reference to the United States Pharmacopoeia. Amoxicillin and clavulanic acid contents for oral suspensions were determined immediately after reconstitution and 7 days thereafter to determine their stability during the prescription period. On day seven, 23.1% (3 out of 13) of amo...Continue Reading

References

Jun 27, 2001·Lancet·R B TaylorJ A Kolawole
Jul 1, 1963·Journal of Pharmaceutical Sciences·E BROCHMANN-HANSSEN, J C MEDINA
May 3, 2008·Biotechnology Advances·Parag S SaudagarRekha S Singhal
Jul 11, 2008·Journal of Clinical Pharmacy and Therapeutics·S KyriacosO Khouzam
May 11, 2010·Cold Spring Harbor Perspectives in Biology·Thomas J SilhavySuzanne Walker
May 25, 2012·Médecine et maladies infectieuses·A DelepierreA Carpentier
Aug 21, 2013·BMJ Open·Tariq AlmuzainiHelen Sammons
Sep 5, 2013·The Journal of Antibiotics·Mark S ButlerMatthew A Cooper
Nov 30, 2013·British Journal of Clinical Pharmacology·Atholl Johnston, David W Holt
Apr 22, 2015·The American Journal of Tropical Medicine and Hygiene·Ifeyinwa FadeyiHarparkash Kaur
Feb 26, 2016·Journal of Pharmaceutical Sciences·Boris Shekunov, Eda Ross Montgomery

❮ Previous
Next ❯

Software Mentioned

UVWIN
OpenLAB
Excel MS
Statistical Package for Social Scientists ( SPSS )

Related Concepts

Related Feeds

Beta-lactamase Inhibitors (ASM)

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Beta-lactamase Inhibitors

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Related Papers

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
A HuttnerJ W Mouton
The Medical Letter on Drugs and Therapeutics
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
A L Barry, P C Fuchs
© 2021 Meta ULC. All rights reserved