Quality assurance tool for organ at risk delineation in radiation therapy using a parametric statistical approach.

Medical Physics
Cheukkai B HuiJeffrey V Siebers

Abstract

To develop a quality assurance (QA) tool that identifies inaccurate organ at risk (OAR) delineations. The QA tool computed volumetric features from prior OAR delineation data from 73 thoracic patients to construct a reference database. All volumetric features of the OAR delineation are computed in three-dimensional space. Volumetric features of a new OAR are compared with respect to those in the reference database to discern delineation outliers. A multicriteria outlier detection system warns users of specific delineation outliers based on combinations of deviant features. Fifteen independent experimental sets including automatic, propagated, and clinically approved manual delineation sets were used for verification. The verification OARs included manipulations to mimic common errors. Three experts reviewed the experimental sets to identify and classify errors, first without; and then 1 week after with the QA tool. In the cohort of manual delineations with manual manipulations, the QA tool detected 94% of the mimicked errors. Overall, it detected 37% of the minor and 85% of the major errors. The QA tool improved reviewer error detection sensitivity from 61% to 68% for minor errors (P = 0.17), and from 78% to 87% for major error...Continue Reading

References

Oct 21, 2010·Journal of Medical Imaging and Radiation Oncology·Michael G JamesonPeter E Metcalfe
Jan 17, 2012·International Journal of Radiation Oncology, Biology, Physics·Lakshmi SantanamWalter Bosch
May 16, 2012·International Journal of Radiation Oncology, Biology, Physics·Jennifer BreunigJohn C Roeske
Jul 31, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ebbe L LorenzenCarsten Brink
Apr 17, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Andrea C LoRobert Olson
May 3, 2014·Medical Physics·Gregory SharpJinzhong Yang
Sep 14, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gary V WalkerClifton David Fuller
Jul 29, 2015·Practical Radiation Oncology·Brett W CoxLouis Potters
May 14, 2016·Journal of Medical Imaging and Radiation Oncology·Shalini K VinodLois C Holloway
Oct 13, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Shalini K VinodLois C Holloway
Feb 15, 2017·Medical Physics·Hamidreza NourzadehJeffrey V Siebers

❮ Previous
Next ❯

Citations

Apr 28, 2021·Physics in Medicine and Biology·Pavlos PapaconstadopoulosTomas Janssen
May 17, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Nicola MaffeiGabriele Guidi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.

Related Papers

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology
Arvind Kumar ShuklaS C Sharma
Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health
E A McGlynnS M Asch
British Journal of Plastic Surgery
© 2022 Meta ULC. All rights reserved