Quality improvement of adaptive optics retinal images using conditional adversarial networks

Biomedical Optics Express
Wanyue LiGuohua Shi

Abstract

The adaptive optics (AO) technique is widely used to compensate for ocular aberrations and improve imaging resolution. However, when affected by intraocular scatter, speckle noise, and other factors, the quality of the retinal image will be degraded. To effectively improve the image quality without increasing the imaging system's complexity, the post-processing method of image deblurring is adopted. In this study, we proposed a conditional adversarial network-based method for directly learning an end-to-end mapping between blurry and restored AO retinal images. The proposed model was validated on synthetically generated AO retinal images and real retinal images. The restoration results of synthetic images were evaluated with the metrics of peak signal-to-noise ratio (PSNR), structural similarity (SSIM), perceptual distance, and error rate of cone counting. Moreover, the blind image quality index (BIQI) was used as the no-reference image quality assessment (NR-IQA) algorithm to evaluate the restoration results on real AO retinal images. The experimental results indicate that the images restored by the proposed method have sharper quality and higher signal-to-noise ratio (SNR) when compared with other state-of-the-art methods, wh...Continue Reading

References

Nov 14, 1997·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J LiangD T Miller
Sep 8, 1998·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·F Vargas-MartínP Artal
Oct 3, 2002·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Larry N ThibosXin Hong
Aug 28, 2004·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Julian C ChristouDavid R Williams
Apr 13, 2007·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Stephen A BurnsDaniel X Hammer
Nov 17, 2007·Optics Letters·Stephen A BurnsSalvador Bara
May 6, 2002·Optics Express·Austin RoordaMelanie Campbell
Apr 17, 2006·Optics Express·Daniel X HammerStephen A Burns
Jul 5, 2011·Investigative Ophthalmology & Visual Science·Hongxin SongStephen A Burns
May 15, 2013·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Robert F CooperJoseph Carroll
Apr 15, 2014·The British Journal of Ophthalmology·Manickam Nick MuthiahLyndon da Cruz
Sep 15, 2015·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Letizia Mariotti, Nicholas Devaney
Aug 16, 2016·Advances in Experimental Medicine and Biology·Yi HeYudong Zhang
Jan 4, 2018·Biomedical Optics Express·Xiao FeiYudong Zhang

❮ Previous
Next ❯

Citations

May 29, 2021·Scientific Reports·Laura K Young, Hannah E Smithson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.