Quality of Life After Combined Endonasal Endoscopic Odontoidectomy and Posterior Suboccipital Decompression and Fusion

World Neurosurgery
Malte OttenhausenTheodore H Schwartz

Abstract

Basilar invagination can result from systemic diseases that can weaken structural integrity of the craniocervical junction. Definitive treatment often requires ventral decompression and posterior decompression and fusion. Endonasal odontoidectomy is a relatively new minimal access procedure; quality of life (QOL) after this procedure has not been reported. We reviewed a consecutive database of endonasal odontoidectomy cases and identified patients having posterior decompression and fusion. Two QOL questionnaires were administered postoperatively: Sino-Nasal Outcome Test and 36-Item Short Form Survey. Comparisons with other endonasal or Chiari procedures were performed. The study comprised 14 patients; 79% had Chiari malformation in addition to basilar invagination. Mean follow-up was 17.2 months. Symptomatic improvement occurred in 78.6% after surgery. Average postoperative Sino-Nasal Outcome Test scores were 39.2 ± 17.93, with worst scores in areas related to fatigue and sleep patterns but not nasal function. 36-Item Short Form Survey scores were lower in areas of physical function and general health but better for emotional health and pain. Compared with patients undergoing Chiari malformation surgery without endonasal odonto...Continue Reading

References

Jan 1, 1995·British Journal of Neurosurgery·H A Crockard
Feb 1, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jay F PiccirilloMichele L Richards
Apr 17, 2002·Acta neurochirurgica·A AlfieriM Tschabitscher
Oct 6, 2005·Clinical Neurology and Neurosurgery·Venetia TsaraAristidis Kazis
May 12, 2007·Neurosurgical Review·Andrea MessinaManfred Tschabitscher
Jul 7, 2007·Zentralblatt für Neurochirurgie·M StoffelB Meyer
Nov 15, 2007·American Journal of Rhinology·Jayakar V NayakCarl H Snyderman
Jul 2, 2010·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Ziv Gil, Dan M Fliss
Dec 3, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jens GemptMichael Stoffel
Feb 22, 2012·Archives of Otolaryngology--head & Neck Surgery·Avraham AbergelZiv Gil
Sep 1, 2015·Journal of Neurosurgery. Spine·David A BesachioLubdha M Shah
Jun 28, 2016·Current Pain and Headache Reports·Nandor K PinterLaszlo Mechtler
Jul 22, 2016·Clinical Neurology and Neurosurgery·Michael F ShriverPablo F Recinos
Oct 30, 2016·Journal of Neurosurgery. Pediatrics·Aditya VedantamAndrew Jea
Feb 23, 2017·Journal of Neurosurgical Anesthesiology·Matthew A SextonJeffrey J Pasternak
Mar 28, 2017·The Spine Journal : Official Journal of the North American Spine Society·Peter G PassiasUNKNOWN International Spine Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.