Quality of life after potentially curative treatment for locally advanced rectal cancer

Annals of Surgical Oncology
Gabriella PalmerTorbjörn Holm

Abstract

Patients with locally advanced rectal cancer have a poor prognosis and the early and late postoperative morbidity is high. The aim of this study was to assess health-related quality of life (HRQL) in patients treated with extensive surgical resections for locally advanced rectal cancer and to compare the results with those in patients treated for primarily resectable rectal cancer. Between 1991 and 2003, 142 patients with locally advanced rectal cancer had an extensive resection at the Karolinska Hospital in Stockholm, Sweden. A HRQL assessment with the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-CR38 questionnaires was performed in patients alive and disease free in 2005. The results were compared with an age- and sex-matched reference group of patients with primarily resectable rectal cancer having had total mesorectal excision alone. The study group of 43 patients (81% of eligible) scored clinically and statistically significantly lower in global quality of life, role function, physical function, social function, and body image and reported a higher degree of pain and fatigue compared with the reference group of 80 patients. In the study group, men scored lower than women in global qual...Continue Reading

References

Jun 6, 1985·The New England Journal of Medicine·UNKNOWN Gastrointestinal Tumor Study Group
Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D OsobaJ Pater
Nov 3, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K KobayashiK Yoshida
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M A SprangersN K Aaronson
Mar 29, 2001·Journal of Surgical Oncology·D Turns
May 25, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G H MannaertsT Wiggers
Jun 8, 2001·Diseases of the Colon and Rectum·G H MannaertsT Wiggers
Jun 22, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J Camilleri-Brennan, R J Steele
Jul 4, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P M Fayers
Oct 24, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M G GurenK E Giercksky
Dec 12, 2001·The British Journal of Surgery·J Camilleri-Brennan, R J Steele
Dec 14, 2001·Diseases of the Colon and Rectum·J Garcia-AguilarD A Rothenberger
Jun 14, 2002·International Journal of Radiation Oncology, Biology, Physics·Vincenzo ValentiniMaurizio Cosimelli
Jul 2, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·N R MaiseyD Cunningham
Apr 5, 2003·Annals of Surgery·Dieter HahnloserAlan Horgan
Aug 2, 2003·Annals of Surgery·Jutta EngelDieter Hölzel
Aug 20, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T WiggersH J T Rutten
Jan 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Philippe RauchFrancis Guillemin
Sep 1, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R BakxF A N Zoetmulder
Mar 9, 2005·International Journal of Radiation Oncology, Biology, Physics·Abdelkarim S AllalSabine Bieri
Mar 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Corrie A M MarijnenAnne M Stiggelbout
Mar 24, 2005·Diseases of the Colon and Rectum·Kirsten M BoyleIan Eardley
Jun 28, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G PalmerT Holm
Jan 18, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M T EriksenUNKNOWN Norwegian Gastrointestinal Cancer Group
Mar 15, 2006·Diseases of the Colon and Rectum·Johan PollackAnders Mellgren
Oct 21, 2006·The British Journal of Surgery·J PollackA Mellgren
May 25, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S GujralUNKNOWN European Organisation for Research and Treatment of Cancer Quality of Life Group
Jul 7, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S G LarsenK-E Giercksky

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Citations

Jan 1, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K HorisbergerP Kienle
Feb 25, 2014·Journal of Gastrointestinal Cancer·Koh Ye XinMelissa Ching Ching Teo
Apr 8, 2009·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·C-T Germer, C Isbert
Jan 16, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sue-Anne McLachlanSamuel Y Ngan
Jan 1, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M B NielsenT Holm
Jun 22, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H V ThaysenS Laurberg
Mar 12, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·D P HarjiJ Brown
Jan 6, 2015·Journal of Surgical Oncology·Deena P HarjiJulia Brown
Jan 1, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H V ThaysenS Laurberg
Aug 13, 2013·International Journal of Cancer. Journal International Du Cancer·Marjan J TraaHarm J T Rutten
May 15, 2015·Psycho-oncology·Catherine BenedictChristian Nelson
Jul 26, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Morten BrændengenBengt Glimelius
Aug 12, 2014·International Journal of Surgery Case Reports·Daniel Fernández-MartínezHerminio Sánchez-Farpón
Aug 15, 2014·Journal of Palliative Medicine·Katie H StowersJillian Gustin
Jul 9, 2014·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Letácio José Freire SantosAlcione Miranda dos Santos
Oct 17, 2009·Annals of Surgical Oncology·Fabio PacelliGiovanni B Doglietto
Apr 17, 2012·Expert Review of Anticancer Therapy·Georg F WeberHelmut Friess
Mar 10, 2016·Diseases of the Colon and Rectum·Nick J BattersbyUNKNOWN United Kingdom Low Anterior Resection Syndrome Study Group
Jul 31, 2009·Expert Opinion on Pharmacotherapy·Rossana BerardiStefano Cascinu
Jan 15, 2015·Diseases of the Colon and Rectum·Ricardo G OrsiniHarm J T Rutten

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