Quality of life after surgery for intractable partial epilepsy in children: a cohort study with controls

Epilepsy Research
Mohamad A MikatiYoussef Comair

Abstract

Investigate if quality of life (QOL) normalizes on long-term follow-up after surgery for partial epilepsy in children. This is a cohort study with controls in which a consecutive cohort of nineteen 2-14-year-old children who underwent focal resections for intractable partial seizures between 1996 and 2006, were matched with 19 non-surgery intractable partial epilepsy patients, and with 19 healthy subjects. The two epilepsy groups were matched for age, sex, socio-economic status (SES), cognitive level, seizure type, and seizure frequency. The healthy group was matched with the two epilepsy groups for age, sex, SES, and cognitive level. QOL was assessed using the QOLCE (Quality of Life in Childhood Epilepsy Questionnaire). In the surgery group (follow-up 3.84+/-2.26 years), 78.9% had Engel class-I versus 21.1% in non-surgery (p=0.01) (follow-up 3.44+/-2.95 years). Surgery patients were similar to healthy subjects in the social, emotional, cognitive, behavioral, and overall QOL (p>0.05) but had lower scores in the total QOL, physical, and health domains (p<0.05). Surgery patients scored better than non-surgery in the behavioral domain and the HASES (Hague Side Effects Scale) score (p<0.05). Non-surgery patients scored worse than h...Continue Reading

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Citations

Jun 1, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dario J EnglotKurtis I Auguste
Sep 29, 2011·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Carmen SoriaGeorges Dellatolas
Oct 29, 2011·Epilepsia·Luigi D'ArgenzioJ Helen Cross
Apr 3, 2012·Journal of Neurosurgery. Pediatrics·Michael Anthony CilibertoMatthew D Smyth
Jun 19, 2013·Journal of Neurosurgery. Pediatrics·Dario J EnglotKurtis I Auguste
Aug 28, 2014·Pediatric Neurology·Mohammed IlyasHarry Chugani
Sep 23, 2014·Journal of Neurosurgery. Pediatrics·Gregory W AlbertJames T Rutka
Aug 16, 2014·Journal of Neurosurgery. Pediatrics·Dario J EnglotKurtis I Auguste
Jul 24, 2012·Developmental Medicine and Child Neurology·Luigi D'ArgenzioJ Helen Cross
May 6, 2015·Epilepsia·Klajdi Puka, Mary Lou Smith
Nov 12, 2013·Epilepsy & Behavior : E&B·Jamal M Al-Khateeb, Anas J Al-Khateeb
Nov 12, 2019·Developmental Medicine and Child Neurology·Puneet JainUNKNOWN Pepsqol Study Team
Oct 27, 2017·The New England Journal of Medicine·Rekha DwivediManjari Tripathi
Apr 13, 2018·Epilepsy Currents·Prakash Kotagal
Mar 16, 2017·Journal of Neurosurgery. Pediatrics·Hiroshi HosoyamaKazunori Arita
Oct 20, 2018·Neurosurgery·Georgios A MaragkosKonstantinos S Mylonas
Aug 10, 2012·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Karl O NakkenArild Egge
Jul 22, 2020·World Neurosurgery·Claudia M Kuzan-FischerCaitlin E Hoffman
Sep 3, 2020·Epilepsy Research·Lara MrouehAmal Al-Hajje
Mar 22, 2020·Epilepsy & Behavior : E&B·Suenia Timotheo Figueiredo LealAna Paula Andrada Hamad

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