Quality of Life after Surgical Ablation of Persistent Atrial Fibrillation: A Prospective Evaluation

Heart, Lung & Circulation
Alexander ChernyavskiyAlexander Romanov

Abstract

To compare the quality of life (QoL) of patients with persistent atrial fibrillation (AF) and ischaemic heart disease after modified mini-maze (MM) procedure or pulmonary vein isolation (PVI) using radiofrequency ablation (RFA) with patients in the control group (coronary artery bypass graft [CABG]) alone. In this prospective randomised study, we included 95 patients with persistent AF and coronary heart disease who underwent open-heart surgery combined with intraoperative irrigated RFA (irrRFA). Patients were randomly assigned to three groups: CABG and PVI using irrRA (CABG+PVI, n=31), CABG and MM procedure using irrRA (CABG+MM, n=30), and isolated CABG (CABG alone, n=34). All patients received implantable loop recorders (ILRs). Patient QoL was assessed using the Short Form 36 (SF-36) preoperatively, and one and two years post-operatively. The study primary end point was freedom from AF one year after operation, measured by implantable loop recorders (ILRs); secondary endpoint included long-term clinical outcomes. No reoperations or hospital mortalities were recorded. Mean follow-up was 14.4±9.7 months. The percentages of patients free from AF determined by ILR were 80%, 86.2%, and 44.1% in the CABG+PVI, CABG+MM, and in the CA...Continue Reading

References

Jul 14, 2001·Journal of Cardiovascular Pharmacology and Therapeutics·C J HowesM D Ezekowitz
Nov 27, 2008·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Deirdre A Lane, Gregory Y H Lip
Feb 28, 2014·Interactive Cardiovascular and Thoracic Surgery·Alexander CherniavskyAlexander Karaskov

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Citations

Aug 24, 2016·The Cochrane Database of Systematic Reviews·Mark D HuffmanS C Malaisrie
Sep 11, 2020·The Journal of Cardiovascular Surgery·Nora GoebelUlrich F Franke
Oct 12, 2021·Interactive Cardiovascular and Thoracic Surgery·Bart MaesenJos G Maessen

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