Quality of life after surgical treatment of primary intramedullary spinal cord tumors in children

Journal of Neurosurgery. Pediatrics
Christian SchneiderKarl F Kothbauer

Abstract

Presently, the best available treatment for intramedullary spinal cord tumors (IMSCTs) in children is microsurgery with the objective of maximal tumor removal and minimal neurological morbidity. The latter has become manageable with the development and standard use of intraoperative neurophysiological monitoring. Traditionally, the perioperative neurological evaluation is based on surgical or spinal cord injury scores focusing on sensorimotor function. Little is known about the quality of life after such operations; therefore, this study was designed to investigate the impact of surgery for IMSCTs on the quality of life in children. Twelve consecutive pediatric patients treated for IMSCT were included in this retrospective fixed cohort study. A multidimensional questionnaire-based quality of life instrument, the Pediatric Quality of Life Questionnaire version 4 (PedsQL 4.0), was chosen to analyze follow-up data. This validated instrument particularly allows for a comparison between a patient cohort and a healthy pediatric sample population. Of 11 mailed questionnaires (1 patient had died of progressive disease), 10 were returned, resulting in a response rate of 91%. There were 8 low-grade lesions (5 pilocytic astrocytomas, 1 ga...Continue Reading

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Citations

Aug 4, 2015·Neurosurgical Focus·Matthew K TobinAnkit I Mehta
Oct 30, 2016·Journal of Neurosurgery. Pediatrics·Aditya VedantamAndrew Jea
May 10, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Faris ShweikehJ Patrick Johnson
Oct 24, 2019·Journal of Neuro-oncology·Steven S CareyIbrahim Qaddoumi
Jul 22, 2018·Journal of Neurosurgery. Pediatrics·Tej D AzadGerald A Grant
Jul 28, 2021·Neurosurgical Review·Nikolaos VlachosGeorge A Alexiou

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Software Mentioned

GraphPad Prism
PedsQL

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