Quality of life after videoscopic left cardiac sympathetic denervation in patients with potentially life-threatening cardiac channelopathies/cardiomyopathies

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Ryan M AntielMichael J Ackerman

Abstract

Left cardiac sympathetic denervation (LCSD) provides an additive or potentially alternative treatment option for patients with life-threatening cardiac channelopathies/cardiomyopathies. We sought to examine the effects of LCSD on quality of life (QOL). From November 2005 to May 2013, 109 patients who underwent LCSD were subsequently sent postoperative QOL surveys. Of 109 patients, 8 (7%) could not be contacted. Of the remaining 101 patients, 62 returned surveys (response rate 61%). There were an average of 4.1 ± 1.8 self-reported side effects immediately after LCSD. The most common anticipated side effects included unilateral hand dryness, color or temperature variance between sides of the face, and abnormal sweating. Although parent-reported pediatric physical QOL scores were lower than national norms, there were no differences in psychosocial QOL or disability scores (P = .09 and .33, respectively). QOL scores for adult patients were not significantly different from a US normative sample. Adult LCSD patients reported less disability than a US normative sample (P < .01). There was no correlation between QOL scores and the presence of anticipated side effects. However, among the subset of pediatric patients who continued to rec...Continue Reading

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Citations

Sep 27, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Peter J Schwartz
Nov 9, 2016·Korean Circulation Journal·Yongkeun Cho
Dec 25, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Tadanobu IrieMarmar Vaseghi
Apr 12, 2019·Frontiers in Cardiovascular Medicine·Veronica DusiPeter J Schwartz
Jul 18, 2020·Nature Reviews. Disease Primers·Peter J SchwartzArthur A M Wilde
Mar 25, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Chance M WittChristopher J McLeod
Apr 27, 2016·The Journal of Physiology·Kalyanam ShivkumarDouglas P Zipes
Jul 17, 2020·Frontiers in Physiology·Maria Teresa La RoverePeter J Schwartz
Oct 30, 2020·Asian Cardiovascular & Thoracic Annals·Savvas LampridisNikolaos Panagiotopoulos
Nov 18, 2020·Circulation. Arrhythmia and Electrophysiology·Talha NiazMichael J Ackerman
Nov 28, 2017·Cardiac Electrophysiology Clinics·Peter J SchwartzArthur A M Wilde
Aug 24, 2019·JACC. Clinical Electrophysiology·Ching ZhuKalyanam Shivkumar

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