Quality of life and functional outcome of male patients with bladder-prostate rhabdomyosarcoma treated with conservative surgery and brachytherapy during childhood

Brachytherapy
Hélène MartelliChristine Haie-Meder

Abstract

The aim of this study was to report the long-term results of a conservative local treatment of male patients with bladder-prostate rhabdomyosarcoma (BPRMS) focusing on their outcome and quality of life (QoL). From 1991 to 2007, 27 male patients were treated by a single team, according to the ongoing European protocols. Surgical procedure was partial cystectomy or partial prostatectomy or both, followed by low-dose-rate interstitial brachytherapy. Three patients died of metastases and two were excluded; 22 patients, who were long-term survivors with their bladder, received a QoL questionnaire derived from the International Workshop on BPRMS. Urodynamic studies were performed when patients had abnormal continence. Median age at surgery was 24 months (14 months-11 years). Median followup after surgery was 10 years (5-21 years); 18 male patients (77%) completed the questionnaire at a median age of 13 years (7-25 years); 13 considered themselves as having a normal QoL, with normal urinary continence (9 of 13) or very rare diurnal dribbling (4 of 13). Four male patients had frequent diurnal dribbling requiring protection for three of them and one was submitted to intermittent catheterism for a postoperative neurogenic bladder. Urodyn...Continue Reading

References

Jun 21, 2002·European Urology·M TheunisJ Vande Walle
Jan 10, 2003·BJU International·E W GerharzC R J Woodhouse
Jun 14, 2003·Prostate Cancer and Prostatic Diseases·R Ashlock, P A S Johnstone
Mar 29, 2006·Journal of Pediatric Surgery·Andrea Hayes-JordanKevin P Lally
Sep 6, 2006·The Journal of Urology·Fernando A FerrerMartin A Koyle
Oct 31, 2006·The Journal of Urology·Beverly RaneyUNKNOWN Italian Soft-Tissue Sarcoma Cooperative Group
Jul 31, 2009·Journal of Pediatric Urology·Hsi-Yang WuRichard B Womer
Dec 14, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Yves RéguerreDaniel Orbach
May 21, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·C Haie-MederO Oberlin

❮ Previous
Next ❯

Citations

Oct 30, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jörg FuchsGuido Seitz
Jan 9, 2019·Nature Reviews. Disease Primers·Stephen X SkapekDouglas S Hawkins
Mar 10, 2020·F1000Research·Roberto Iglesias LopesArmando J Lorenzo
Mar 13, 2021·Surgical Oncology Clinics of North America·Timothy N Rogers, Roshni Dasgupta

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.