Quality of life and lung function after pleurectomy/decortication for malignant pleural mesothelioma.

Interactive Cardiovascular and Thoracic Surgery
Toru NakamichiSeiki Hasegawa

Abstract

Impact of pleurectomy/decortication (P/D) on quality of life (QOL) is not widely reported. We investigated QOL and lung function after P/D. A single-centre, retrospective cohort study was performed among patients who underwent P/D for malignant mesothelioma between June 2014 and June 2018 at Hyogo College of Medicine. Data at 4 points before and 3, 6 and 12 months on QOL and lung function were evaluated with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and pulmonary function tests. Forty-five out of 65 patients completed SF-36. Physical function and role physical decreased from 78 to 65 and 69 to 41 and did not recover. Body pain decreased from 74 to 52. It increased to 62 at 12 months but was lower than before. General health perceptions, vitality and social function decreased from 56 to 49, 50 to 47 and 63 to 50, respectively, but returned to baseline. Role emotional decreased from 75 to 54, then once increased to 63, but decreased again to 58. Mental health tended to improve from 58 to 70. Thirty-eight patients out of 45 completed pulmonary function tests. Forced vital capacity and forced expiratory volume in 1 s decreased from 98% to 61% and 93% to 67% and did not increase. Right-sided surgery or comp...Continue Reading

References

Nov 17, 1998·Journal of Clinical Epidemiology·S FukuharaK Kurokawa
Mar 4, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anne S TsaoHedy Lee Kindler
Jun 23, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Servet BölükbasJoachim Schirren
Oct 17, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Valerie W RuschUNKNOWN IASLC Staging Committee
Apr 26, 2014·The Clinical Respiratory Journal·Gürhan ÖzAdnan Sayar
Dec 11, 2017·The Annals of Thoracic Surgery·Sahar A SaddoughiShanda H Blackmon
Oct 8, 2018·Journal of Surgical Oncology·Maaike van GerwenEmanuela Taioli
Jan 15, 2019·Seminars in Thoracic and Cardiovascular Surgery·Seiki HasegawaTakashi Nakano

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