Quality of life and mortality from a nephrologist's view: a prospective observational study.

BMC Nephrology
Seung Seok HanHo Jun Chin

Abstract

Although health-related quality of life (HRQOL) is a potential independent predictor of mortality, nephrologists have shown little interest in HRQOL with respect to mortality in chronic kidney disease (CKD). The aim of this article is to evaluate the impact of HRQOL on mortality in the elderly, who are likely to develop or already have CKD. Among 1,000 randomly sampled participants aged more than 65 years (sourced from the Korean Longitudinal Study on Health and Ageing), 944 subjects were evaluated for HRQOL. HRQOL was assessed using a 36-item Short-Form health survey (SF36). A cumulative survival rate was calculated according to tertiles of SF36 scores and classified by the presence of CKD (estimated GFR <60 ml/min/1.73 m2). Among 944 subjects, 46.6% had CKD. CKD patients had lower total and physical component scores compared with subjects without CKD. The 3-year cumulative survival rate was 90.0% (non-CKD vs. CKD: 92.6% vs. 87.4%, P = 0.005 by log rank test). After adjusting for multiple variables, a reduced SF36 score (physical and mental components) was a strong predictor of all-cause mortality. Physical components were consistently able to predict mortality after CKD classification, but mental components were statistically...Continue Reading

References

May 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A J CollinsP Keshaviah
Mar 1, 1973·Journal of Health and Social Behavior·G L Maddox, E B Douglass
Jul 1, 1993·Journal of the American Society of Nephrology : JASN·P L KimmelR A Peterson
May 29, 1993·BMJ : British Medical Journal·A M GarrattI T Russell
May 1, 1997·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·S L BernardM G Ory
Aug 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P B DeOreo
Jul 2, 1998·Kidney International·P L KimmelJ H Veis
Feb 17, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J A Diaz-BuxoJ M Lazarus
Dec 1, 2001·Journal of the American Society of Nephrology : JASN·Kamyar Kalantar-ZadehMichael H Humphreys
Jun 29, 2002·Journal of the American Academy of Nurse Practitioners·Mary Jo Goolsby
Mar 4, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Antonio Alberto LopesUNKNOWN Worldwide Dialysis Outcomes and Practice Patterns Study Committee
Apr 5, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rachel L PerlmanRajiv Saran
Sep 6, 2005·International Urology and Nephrology·Kamyar Kalantar-Zadeh, Mark Unruh
May 12, 2006·Journal of the American Geriatrics Society·David A DorrPaul D Clayton
Feb 6, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·UNKNOWN KDOQI
Aug 19, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Mengli TongMohamed E Suliman
Nov 8, 2007·JAMA : the Journal of the American Medical Association·Josef CoreshAndrew S Levey
Mar 29, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ho Jun ChinDong-Wan Chae
Aug 1, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Salim K MujaisFrederic O Finkelstein

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Citations

Mar 26, 2014·Postgraduate Medical Journal·Osasuyi Iyasere, Edwina A Brown
Sep 20, 2012·The American Journal of the Medical Sciences·Tao PengXiangdong Yang
Dec 24, 2010·Kidney International·Debbie S GipsonAaron L Friedman
Oct 11, 2014·Journal of Religion and Health·Chutikarn ChatrungKwanjai Amnatsatsue

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Methods Mentioned

BETA
KLoSHA
light microscopy
coronary artery bypass

Software Mentioned

SPSS

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