Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest

Journal of Endocrinological Investigation
S CarusoA Cianci

Abstract

The aim of the study was to evaluate the effects of dienogest (DNG) on quality of life (QoL) and sexual function of women affected by endometriosis pain. Fifty-four women constituted the study group and were given 2 mg/daily DNG; 48 women were given non-steroidal anti-inflammatory drugs and constitut ed the control group. To define the endometriosis-associated pelvic pain, the Visual Analogic Scale (VAS) was used. The Short Form-36 (SF-36), the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) were used to assess the QoL, the sexual function and the sexual distress, respectively. The study included two follow-ups at 3 and 6 months. Pain improvement was observed in the study group at 3 (p < 0.05) and 6 months (p < 0.001) of treatment. At the 1st follow-up, women reported QoL improvements in some functions (p < 0.05); at the 2nd follow-up, they reported improvement in all categories (p < 0.001). The FSFI score did not change at the 1st follow-up (p = NS). On the contrary, at the 2nd follow-up, it improved with respect to the baseline (p < 0.05). At the 2nd follow-up, the FSFI score had risen to 27.8 (p < 0.001) and the FSDS score had dropped to 11.3 (p < 0.001). No change was observed in the control ...Continue Reading

References

Nov 26, 1998·Drugs·R H Foster, M I Wilde
Dec 28, 1999·European Journal of Pharmacology·M NakamuraT Oikawa
May 25, 2004·Journal of Advanced Nursing·Elaine Denny
Jun 28, 2005·Human Reproduction·Stephen KennedyUNKNOWN ESHRE Special Interest Group for Endometriosis and Endometrium Guideline Development Group
Sep 17, 2005·Journal of Clinical Nursing·Annette Huntington, Jean A Gilmour
Jan 21, 2006·The Journal of Sexual Medicine·Rosemary BassonWillibrord Weijmar Schultz
May 15, 2007·Fertility and Sterility·Ninet SinaiiPamela Stratton
Apr 3, 2008·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Rossella E NappiFranco Polatti
Oct 24, 2008·Gynecologic and Obstetric Investigation·Marc R Laufer
Nov 18, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rodrigo de P Sepulcri, Vivian F do Amaral
Feb 7, 2009·Reproductive Sciences·Peter A W RogersKrina T Zondervan
Dec 17, 2009·Women's Health·Tasuku Harada, Fuminori Taniguchi
May 7, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Thomas StrowitzkiChristian Seitz
May 11, 2011·Current Pain and Headache Reports·Ja Hyun Shin, Fred M Howard
Jul 2, 2011·Fertility and Sterility·Kelechi E NnoahamUNKNOWN World Endometriosis Research Foundation Global Study of Women's Health consortium
Oct 18, 2013·The Journal of Family Planning and Reproductive Health Care·Lone HummelshojPaolo Vercellini
Nov 28, 2013·Gastroenterology Clinics of North America·Sharon L Stein
Dec 25, 2013·Nature Reviews. Endocrinology·Paolo VercelliniLuigi Fedele
Jan 18, 2014·Human Reproduction·G A J DunselmanUNKNOWN European Society of Human Reproduction and Embryology
Mar 19, 2014·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine
May 9, 2014·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Mariko MiyashitaYutaka Osuga
May 28, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Caterina ExacoustosErrico Zupi
Aug 15, 2014·International Journal of Women's Health·Rossella E NappiJeffrey T Jensen
Dec 3, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Matteo MorottiSimone Ferrero
Jun 13, 2015·Journal of Endocrinological Investigation·S Triunfo, A Lanzone

❮ Previous
Next ❯

Citations

Feb 20, 2016·Journal of Endocrinological Investigation·R Granata
Oct 26, 2016·Journal of Endocrinological Investigation·S CarusoA Cianci
May 15, 2018·Journal of Sex & Marital Therapy·João Paulo Leonardo-PintoDaniela Angerame Yela
Jan 11, 2019·PloS One·Nicolas BourdelMichel Canis
May 14, 2019·Minerva medica·Stefano CianciGiovanni Scambia
Nov 23, 2019·Minerva medica·Valentina L La RosaSimone Ferrero
Nov 16, 2019·Minerva medica·Valentina L La RosaSimone Ferrero
Sep 16, 2017·Expert Opinion on Pharmacotherapy·Laura BuggioPaolo Vercellini
May 8, 2018·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Seon Hwa JeongByung Chul Jee
Jan 20, 2019·Updates in Surgery·Valerio RumoloGiovanni Scambia
Aug 2, 2018·Journal of Obstetrics and Gynaecology of India·Ahmed Mahmoud AbdouAmr Ahmed Abdelrhman
Oct 5, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Anne OppenheimerArnaud Fauconnier
May 20, 2021·Women & Health·Ana María AlcaldeFrancisco Carmona
May 14, 2021·Journal of Minimally Invasive Gynecology·María-Angeles Martínez-ZamoraFrancisco Carmona

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception
S CarusoA Cianci
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Costantino Di CarloGiuseppe Bifulco
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Costantino Di CarloCarmine Nappi
© 2021 Meta ULC. All rights reserved