Quality of Life and Surgical Outcomes After Soft-Tissue Reconstruction of Complex Oncologic Defects of the Spine and Sacrum

The Journal of Bone and Joint Surgery. American Volume
Roisin T DolanHenk Giele

Abstract

Tumor-related spinal surgery has been revolutionized by recent advances in spinal stabilization, modern neuroimaging, and perioperative intensive medicine. This study examines clinical outcomes and factors associated with complications following reconstruction of complex oncologic defects of the spine and sacrum, in an attempt to increase preoperative recognition of high-risk patients with diminished wound-healing capacity and to optimize clinical outcomes in this cohort. We performed a retrospective analysis of fifty-five consecutive patients who underwent soft-tissue reconstruction with or without osseous stabilization of defects following spinal or sacral tumor resection at a quaternary referral center over a twelve-year period. Surgical outcomes included the prevalence of postoperative complications and success of wound closure at the latest follow-up. Health-related quality-of-life outcomes were assessed using the EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer 30-Item Core Quality of Life Questionnaire) and SF-36 (Short Form-36) questionnaires. The mean age of the cohort was 46.7 years (range, eighteen to seventy-one years), with a male preponderance (3:1). Soft-tissue reconstructions (n = 70 fla...Continue Reading

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Citations

Nov 4, 2016·Expert Review of Medical Devices·Yuntong MaJack W Jennings
Jul 26, 2018·JBJS Reviews·Aleksander Mika, Addisu Mesfin
Aug 24, 2019·Plastic and Reconstructive Surgery·Alexander F MericliJesse C Selber
Jan 9, 2020·Clinical Spine Surgery : a Spine Publication·Roisin T DolanHenk P Giele
Aug 23, 2020·Plastic and Reconstructive Surgery·Matthew A WrightJason A Spector

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