Quality of life and symptomatic outcome three to five years after laparoscopic Toupet fundoplication in gastroesophageal reflux disease patients with impaired esophageal motility

American Journal of Surgery
F A GranderathR Pointner

Abstract

Many centers practice a tailored approach to laparoscopic antireflux surgery in attempt to prevent postoperative side effects in gastroesophageal reflux disease (GERD) patients with an impaired esophageal motility. As a result of controversial findings reported in literature no worldwide accepted consensus exists regarding the appropriate indication for this tailored approach. The aim of this prospective study was to evaluate quality of life and symptomatic outcome in selected patients for a follow-up of 3 to 5 years. A total of 155 patients with esophageal dismotility underwent laparoscopic Toupet fundoplication (LTF). Basic requirements for surgery included in all patients a detailed evaluation of symptoms and quality of life (Gastrointestinal Quality of Life Index [GIQLI]), esophagogastroduodenoscopy, 24-hour pH monitoring, and esophageal manometry. Patients were evaluated 6 weeks, 3 months, 1 year, and 3 to 5 years after LTF. GERD-related symptoms such as heartburn, regurgitation, dysphagia, or chest pain showed a significant improvement (P <0.05 to 0.001) in all gradings immediately after surgery. During the complete follow-up, a total of 4 patients (2.6%) required laparoscopic redo surgery because of recurrent GERD sympto...Continue Reading

References

Jul 1, 1992·Archives of Surgery·H J SteinT R DeMeester
Feb 1, 1988·Digestive Diseases and Sciences·V F Eckardt
Sep 30, 1998·The British Journal of Surgery·D I Watson, G G Jamieson
Feb 25, 1999·World Journal of Surgery·H SpivakJ G Hunter
Apr 16, 1999·American Journal of Surgery·W S Richardson, J G Hunter
May 5, 1999·World Journal of Surgery·L RydbergL Lundell
Sep 9, 1999·Journal of Clinical Gastroenterology·L L Swanstrom
Feb 12, 2000·American Journal of Surgery·R PointnerT Kamolz
Aug 10, 2000·American Journal of Surgery·T R EubanksC A Pellegrini
Aug 19, 2000·Surgical Endoscopy·C EspositoP Desruelle
Oct 24, 2000·The British Journal of Surgery·J R BessellB Menzies

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Citations

Jul 28, 2011·Langenbeck's Archives of Surgery·Stavros A AntoniouFrank A Granderath
Sep 24, 2005·Surgical Endoscopy·M A Carlson, C T Frantzides
Dec 10, 2009·Surgical Endoscopy·Constantine T FrantzidesAlexander Frantzides
Feb 20, 2004·Current Surgery·Brian E LahmannAdrian Park
Jul 2, 2003·Journal of the American College of Surgeons·Keith S Naunheim
Oct 13, 2006·Current Opinion in Gastroenterology·Jeannie F Savas, Thomas A Miller
Jan 25, 2003·Journal of Clinical Gastroenterology·Frank A GranderathThomas Kamolz
Jun 24, 2003·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Vic Velanovich
Jan 30, 2004·Annual Review of Medicine·Sir Ara Darzi, Yaron Munz
Dec 7, 2013·BMC Surgery·Salvatore ToloneLudovico Docimo
Jul 5, 2007·World Journal of Surgery·Ahmet TurkcaparAcar Tuzuner
Oct 26, 2007·World Journal of Surgery·Eduardo Neubarth Trindade, Manoel Roberto Maciel Trindade
Mar 16, 2011·World Journal of Surgery·Bernard Dallemagne, Silvana Perretta
Sep 10, 2009·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·P Salminen
Jul 27, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M de Souza CuryJ Prado P Moraes-Filho
May 31, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Alexa K StatzLuke M Funk
Oct 13, 2019·World Journal of Surgery·Milena NikolicSebastian F Schoppmann
Sep 2, 2018·Surgical Endoscopy·Milena NikolicSebastian F Schoppmann
Nov 25, 2020·BMJ : British Medical Journal·David A Katzka, Peter J Kahrilas
Nov 26, 2020·Surgical Innovation·Adolfo RenziGianni Barone

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