Quality of life and symptomatic response to gastric neurostimulation for gastroparesis.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Vic Velanovich

Abstract

Gastroparesis can be a difficult problem with patients suffering from nausea, vomiting, bloating, and pain intractable to medical management. Gastric neurostimulation has been developed as an adjunctive treatment for patients with diabetic and idiopathic gastroparesis unresponsive to pharmacologic and dietary treatment. The purpose of this study is to report symptomatic and quality-of-life response to gastric neurostimulation. This study was approved by the institutional review board, and patients had informed consent. The gastric neurostimulation device (Enterra therapy, Medtronic, Inc., Minneapolis, MN, USA) is approved by the Food and Drug Administration under the Humanitarian Device Exemption. Candidates for placement were patients with either idiopathic or diabetic gastroparesis who had symptomatic failure to dietary changes and to prokinetic and antiemetic drugs. Before placement, the patients' symptoms were recorded, and patients completed the Gastrointestinal Symptom Rating Scale (GSRS, three domains: dyspeptic syndrome, indigestion syndrome, and bowel dysfunction syndrome) and the Short Form-36 (SF-36, eight domains: physical functioning, role-physical, role-emotional, bodily pain, vitality, mental health, social funct...Continue Reading

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Citations

Jul 4, 2012·Surgical Endoscopy·Joerg ZehetnerJohn C Lipham
Feb 4, 2016·Expert Review of Gastroenterology & Hepatology·James LangworthyRon Schey
May 10, 2017·Journal of Neurogastroenterology and Motility·Mette W KlingeKlaus Krogh
Nov 14, 2012·The American Journal of Gastroenterology·Michael CamilleriUNKNOWN American College of Gastroenterology
Jun 10, 2009·World Journal of Surgery·Gregory O'GradyJohn A Windsor
Apr 28, 2010·Expert Review of Medical Devices·Humberto C Gonzalez, Vic Velanovich
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Jan 15, 2019·Scandinavian Journal of Gastroenterology·Mattis BekkelundLars Aabakken
May 26, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Mohamed M AbdelfatahQiang Cai
Oct 28, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Abdellah HedjoudjeGuillaume Gourcerol
Aug 13, 2021·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Saad SaleemAbell L Thomas
Sep 6, 2011·The Surgical Clinics of North America·Jack W RostasWilliam O Richards

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