Quality of life in epilepsy: comparison of four preference measures

Epilepsy Research
K Stavem

Abstract

Several specific and general measures are available for the assessment of overall health related quality of life in epilepsy. Few of the commonly used measures provide utility weights for use in cost-utility analyses. This study compares four methods for measuring utility weights: time trade-off (TTO), standard gamble (SG), 15D, end the EuroQol visual analog scale. All patients aged 18-67 years with a diagnosis of epilepsy, who had been admitted to or attended the outpatient clinic at a large county hospital 1987-1994, received a comprehensive questionnaire. From 397 respondents, 82 patients were randomly selected. Most of the 57 patients completing the study generally had well-controlled epilepsy, but were still on anti-epileptic medication. Mean age was 44 years. Fourty-one percent were male and 59% female. The resulting utility weights differed considerably between the measures, both with regard to central tendency and dispersion. Median utility scores: EuroQol visual analog scale 0.75, 15D 0.90, TTO 0.98, SG 0.99. There was a good association between the EuroQol rating scale and the 15D, and a moderate association between SG and TTO. These preference instruments measure different aspects of health-related quality of life an...Continue Reading

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Citations

Jan 6, 2005·The Journal of Behavioral Health Services & Research·Martha ShumwayCynthia L Battle
Jul 27, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Knut StavemKjell B Hellum
Mar 26, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·A Simon PickardDavid H Feeny
Jul 20, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Louis S MatzaBeth L Barber
Jan 12, 2010·International Journal of Technology Assessment in Health Care·Tarja Honkalampi, Harri Sintonen
Dec 1, 2005·Kidney International·Irina GorodetskayaGlenn M Chertow
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Mar 24, 2011·Epilepsia·Robert C KnowltonMeredith Kilgore
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Mar 13, 2010·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Kristina S BoyeAodan Tynan
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Jun 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Demetris Pillas, Caroline Selai
Dec 7, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yvonne Anne MichelKim Rand
May 16, 2020·BMC Medical Research Methodology·Xiuying WangLang Zhuo
May 31, 2020·BMC Public Health·Cyrus AliniaMohammad Ebrahimi
Oct 21, 2018·Health and Quality of Life Outcomes·Knut StavemKim Rand

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