Quality of life in mild dementia: patterns of change in self and caregiver ratings over time

Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina
Marcia Cristina Nascimento DouradoJerson Laks

Abstract

To determine changes over time in self and caregiver ratings of quality of life (QoL) in people with dementia (PwD) and to identify factors associated with changes in QoL ratings. In this longitudinal study, 69 people with mild Alzheimer's disease and their caregivers were assessed at baseline and after 1 year. We examined the association of QoL ratings with the following variables at the two time points: awareness of disease, cognitive status, mood, functionality, neuropsychiatric symptoms, and caregiver burden. Multivariate regression analyses were conducted to examine the contribution of co-factors. At baseline, PwD self-ratings of QoL were associated with caregiver ratings of PwD QoL (p = 0.001). Caregiver ratings were associated with PwD mood (p = 0.001) and self-rated QoL (p = 0.001). After 1 year, caregiver ratings of PwD QoL changed significantly (p = 0.049, d = -0.27), whereas PwD self-ratings did not (p = 0.89, d = 0.09). PwD awareness of disease changed significantly (p = 0.001) at 1 year, having declined in 25.4% and improved in 12.3% of participants. PwD QoL self-ratings were associated with caregiver ratings (p = 0.001). Caregiver ratings of PwD QoL after 1 year were associated with PwD mood (p = 0.029), self-repo...Continue Reading

References

Feb 1, 1988·Biological Psychiatry·G S AlexopoulosC A Shamoian
May 1, 1982·Journal of Gerontology·R I PfefferS Filos
Dec 1, 1980·The Gerontologist·S H ZaritJ Bach-Peterson
May 22, 2002·Psychosomatic Medicine·Rebecca G LogsdonLinda Teri
Sep 21, 2002·Social Psychiatry and Psychiatric Epidemiology·Marcia ScazufcaOsvaldo P Almeida
Apr 4, 2003·International Journal of Geriatric Psychiatry·Constantine G LyketsosPeter Rabins
Mar 22, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·S E StarksteinR G Robinson
Sep 7, 2006·International Journal of Geriatric Psychiatry·Asmus VogelGunhild Waldemar
Mar 24, 2007·International Journal of Geriatric Psychiatry·Juanita HoeGill Livingston
Feb 18, 2010·The Journal of Neuropsychiatry and Clinical Neurosciences·Asmus VogelGunhild Waldemar
Jul 7, 2011·International Psychogeriatrics·Asmus VogelGunhild Waldemar
Mar 22, 2013·Journal of Geriatric Psychiatry and Neurology·Josep L Conde-SalaJosep Garre-Olmo
Apr 9, 2013·International Psychogeriatrics·Maria Fernanda Barroso SousaMarcia Cristina Nascimento Dourado
Apr 10, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Josep L Conde-SalaJosep Garre-Olmo
Oct 24, 2013·International Journal of Geriatric Psychiatry·Linda ClareRobin G Morris
Nov 13, 2013·Journal of Alzheimer's Disease : JAD·Josep L Conde-SalaSecundino Lopez-Pousa
Nov 14, 2013·Journal of the American Medical Directors Association·Hanneke C BeerensUNKNOWN RightTimePlaceCare Consortium
Jan 16, 2014·International Review of Psychiatry·Juanita HoeGill Livingston
Jan 1, 2007·Dementia & Neuropsychologia·Marcia DouradoJerson Laks

❮ Previous
Next ❯

Citations

Aug 29, 2016·Journal of Alzheimer's Disease : JAD·Sara LimaM Graça Pereira
Apr 26, 2018·Dementia and Geriatric Cognitive Disorders·Lara HvidstenHege Kersten
Nov 27, 2018·Aging & Mental Health·Isabel B LacerdaMarcia C N Dourado
Dec 1, 2018·Aging & Mental Health·Rachel Dias Lopes da RosaMarcia Cristina Nascimento Dourado
Jul 15, 2020·International Journal of Geriatric Psychiatry·Tatiana BelfortMarcia Cristina Nascimento Dourado
Apr 1, 2020·Journal of Geriatric Psychiatry and Neurology·Marcela Moreira Lima NogueiraMarcia Cristina Nascimento Dourado
Apr 30, 2019·International Journal of Geriatric Psychiatry·Anthony MartyrUNKNOWN IDEAL programme team
Jun 20, 2020·Journal of Geriatric Psychiatry and Neurology·Nathália R S KimuraMarcia C N Dourado
Aug 12, 2020·International Journal of Qualitative Studies on Health and Well-being·Kirsten ThorsenAud Johannessen
Apr 17, 2018·Journal of Geriatric Psychiatry and Neurology·Nathália R S KimuraMarcia C N Dourado
Aug 9, 2020·Journal of Geriatric Psychiatry and Neurology·Marcia Cristina Nascimento DouradoDaniel C Mograbi
Sep 4, 2020·International Journal of Geriatric Psychiatry·Valeska MarinhoDaniel C Mograbi
Nov 23, 2017·Alzheimer Disease and Associated Disorders·Isabel B LacerdaMarcia C N Dourado
Mar 23, 2021·Journal of Alzheimer's Disease : JAD·Maria Alice Tourinho BaptistaMarcia Cristina Nascimento Dourado

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Alzheimer's Disease : JAD
Maria Fernanda Barroso de SousaMarcia Cristina Nascimento Dourado
International Psychogeriatrics
Maria Fernanda Barroso de SousaMarcia Cristina Nascimento Dourado
Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sandrine AndrieuPLASA group
Dementia and Geriatric Cognitive Disorders
Pierre MissottenOvide Fontaine
© 2022 Meta ULC. All rights reserved