Quality of Life in Patients Suffering from Active Exudative Age-Related Macular Degeneration: The EQUADE Study

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Emilie MatamorosNicolas Leveziel

Abstract

Age-related macular degeneration (AMD) is the main cause of visual loss in the elderly population. With the use of anti-vascular endothelial growth factor, the visual outcomes of exudative AMD patients have been improved. This study was aimed at assessing the quality of life (QoL) of exudative AMD patients treated with ranibizumab and at determining its drivers in a real-life setting. We performed a national, cross-sectional, observational survey based on questionnaires sent to members of French associations relative to AMD between December 2012 and March 2013. Patients suffering from exudative AMD with at least one intravitreal injection of ranibizumab within the last 6 months were included. Demographics, AMD characteristics, visual acuity (VA) and past and ongoing treatments were collected. The 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) was self-administered. A multivariate model was used to identify QoL drivers. 416 questionnaires fulfilled the complete criteria for both QoL and cost analyses. The mean age of exudative AMD patients was 78.0 years and bilateral involvement was reported in 60.4%. The overall mean QoL score was 53.4. Mental health, driving and role difficulties were the most widel...Continue Reading

Citations

Sep 23, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Petra RossouwKatja Hatz
Sep 20, 2020·International Journal of Environmental Research and Public Health·Daniel Caballe-FontanetMiguel Angel Sanchez-Tena
Sep 6, 2020·International Journal of Environmental Research and Public Health·Rituparna GhoshalRoslin Azni Abd Aziz
Mar 18, 2021·International Journal of Retina and Vitreous·Alicia Buffoni RoqueJosé Paulo Cabral de Vasconcellos

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