Quality of life in sarcoidosis: comparing the impact of ocular and non-ocular involvement of the disease.

Ophthalmic Epidemiology
Leorey N SaliganH Nida Sen

Abstract

To compare the differences in vision and health-related quality of life (HRQOL) of individuals with ocular and non-ocular sarcoidosis; and to examine the impact of specific demographic and clinical factors on the noted differences. A cross-sectional study using non-randomized prospective cohort was conducted at the National Eye Institute (protocol number: 06-EI-0239, NCT00379275) from August 31, 2006 until November 15, 2007. Each participant completed vision and HRQOL questionnaires, the Sarcoidosis Health Questionnaire (SHQ) and the National Eye Institute Visual Function Questionnaire (NEI-VFQ), along with a demographic/environmental exposure survey. Clinical data were collected through an ophthalmic exam as part of the research protocol. The study enrolled 75 biopsy-proven and 20 clinically presumed sarcoidosis participants which were divided into two cohorts, ocular (N = 60) and non-ocular groups (N = 35). The ocular group had significantly lower (P < 0.01) total NEI-VFQ scores compared to the non-ocular group. Multiple linear regression analysis showed that participants with ocular sarcoidosis who had an annual household income of < $50,000 (P < 0.01) had significantly lower total SHQ scores while participants with ocular s...Continue Reading

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Citations

May 28, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·David E VictorsonMarc A Judson
Nov 12, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·David E VictorsonDavid Cella
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Sep 14, 2011·Clinical Reviews in Allergy & Immunology·Roger A LevyIvan Foeldvari
May 6, 2015·Microvascular Research·Gerasimos SiasosDimitris Tousoulis
Jun 4, 2015·International Ophthalmology Clinics·Sarju Patel
Jun 26, 2020·Seminars in Respiratory and Critical Care Medicine·Ogugua Ndili Obi
Oct 9, 2019·JMIR Public Health and Surveillance·Elizabeth GolembiewskiJoshua R Vest

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