Quality-of-life issues in survivors to anaphylactic reactions to drugs

Allergy
I BaiardiniA Romano

Abstract

The aim of this cross-sectional observational study was to explore quality of life and well-being in patients with drug-induced anaphylaxis. Two validated tools were used: the Drug Hypersensitivity Quality-of-Life Questionnaire (DrHy-Q) and the Psychological General Well-Being Index (PGWBI). Sixty-five patients (13 males) underwent data analysis. The mean DrHy-Q score was 62.82 ± 12.1. Mean PGWBI score was 64.03 ± 17.66. DrHy-Q score was significantly correlated with PGWBI total score (r = -0.314; P = 0.011) and with the following domains: Anxiety (r = -0.260; P = 0.036), Depressed mood (r = -0.406; P = 0.001), Positive well-being (r = -0.251; P = 0.004), and General Health (r = -0.352; P = 0.004). Compared with the Italian reference population, patients had a significantly reduced PGWBI total and domain score. Our results highlight for the first time how impaired HRQoL and distress commonly feature in survivors to anaphylactic reactions to drug.

References

Jul 11, 2006·Current Opinion in Allergy and Clinical Immunology·Joanne N G Oude Elberink
Nov 16, 2006·Health and Quality of Life Outcomes·Enzo GrossiGiovanni Apolone
Mar 5, 2011·The Journal of Allergy and Clinical Immunology·Antonino RomanoMiguel Blanca
Apr 5, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ilaria BaiardiniUNKNOWN DrHy-Q PROs Research Italian Group
Oct 15, 2013·Allergy·S S PanesarUNKNOWN EAACI Food Allergy and Anaphylaxis Group

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Citations

May 6, 2016·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Leàn RolfesEugène van Puijenbroek
Dec 14, 2019·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Leàn RolfesEugène van Puijenbroek
Oct 23, 2018·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Yuda ChongpisonJettanong Klaewsongkram
Jun 28, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Rike van EekerenLinda Härmark
Nov 13, 2020·Asia Pacific Allergy·Eunice Dias de CastroJosefina R Cernadas

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