Abstract
The sex, age, medical history, treatment, tobacco use, race risk (SAMe-TT2R2) Score; the sex, age, medical history, treatment, tobacco use, genotype combination (SAMe-TT2G2) Score; and the so-called modified SAMe-TT2R2 scores have been proposed to predict the anticoagulation quality for patients with non-valvular atrial fibrillation (NVAF). The data from a prospective controlled study is used to validate the SAMe-TT2R2 and SAMe-TT2G2 scores in Chinese NVAF patients treated with warfarin and to evaluate the association of factors with time in therapeutic range (TTR) to predict the quality of oral anticoagulation control. A total of 379 patients with NVAF under warfarin treatment for a three-month follow-up were included in this prospective, multicenter study. The quality of oral anticoagulation control was evaluated by the TTR. The TTR was dichotomized for binary logistic regression analysis, using a cutoff point for classification as an inadequate (TTR < 65.0%) control. The 379 NVAF patients had a mean TTR of 58.35 ± 26.33% and median SAMe-TT2R2 and SAMe-TT2G2 scores of 3 and 2, respectively. The discrimination performances of the SAMe-TT2R2 and SAMe-TT2G2 scores for inadequate anticoagulation control (TTR < 65.0%) were poor (c...Continue Reading
References
Feb 7, 2001·Chest·J HirshD Deykin
Aug 18, 2004·Circulation·Donald M Lloyd-JonesEmelia J Benjamin
Nov 23, 2006·Clinical Pharmacokinetics·Suman LalBalram Chowbay
Jun 25, 2008·Blood·Mia WadeliusPanos Deloukas
Oct 29, 2008·Circulation·Stuart J ConnollyUNKNOWN ACTIVE W Investigators
Dec 25, 2009·Circulation. Cardiovascular Quality and Outcomes·Yi WanYongyong Xu
Mar 5, 2010·Clinical Pharmacology and Therapeutics·D VooraB F Gage
Mar 6, 2010·Blood·Nita A LimdiUNKNOWN International Warfarin Pharmacogenetics Consortium
Apr 9, 2010·Clinical Pharmacology and Therapeutics·P LenziniB F Gage
Oct 1, 2011·Expert Opinion on Drug Safety·Heather D EdwardsSusan E Conway
Dec 27, 2011·Pharmacogenetics and Genomics·Shi-Long ZhongShu-Guang Lin
May 15, 2013·Chest·Stavros ApostolakisGregory Y H Lip
Jul 11, 2013·The Journal of Pharmacy and Pharmacology·Han Oll KimHye Sun Gwak
Nov 15, 2013·Thrombosis and Haemostasis·Raffaele De CaterinaJeffrey I Weitz
Dec 20, 2013·European Heart Journal·Laurent AzoulaySamy Suissa
Feb 8, 2014·Thrombosis Research·Ramon S CancinoAdam J Rose
May 13, 2014·European Journal of Clinical Pharmacology·Durga BistaGregory Peterson
Feb 27, 2015·Thrombosis and Haemostasis·Vilhelm SjögrenAnders Själander
Jun 11, 2015·Journal of Stroke·Yun Kyung ParkOh Young Bang
Mar 12, 2016·Current Medical Research and Opinion·José M Lobos-BejaranoUNKNOWN on behalf the PAULA Study Team
Mar 25, 2016·PloS One·Pak Hei ChanChung Wah Siu
Jun 18, 2016·British Journal of Clinical Pharmacology·Salah AbohelaikaFarhad Kamali
Sep 26, 2016·The American Journal of Cardiology·Gregory Y H LipUNKNOWN IMPACT Investigators
Sep 28, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Nijole BernaitisShailendra Anoopkumar-Dukie
Nov 29, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chern-En ChiangShih-Ann Chen
May 10, 2017·International Journal of Cardiology·Jia LiuTong Yin
May 20, 2017·International Journal of Clinical Pharmacy·Sophia LaiFelix K Yam
Aug 3, 2017·Journal of Arrhythmia·Chern-En ChiangWee Siong Teo
Apr 29, 2018·British Journal of Clinical Pharmacology·Gary TseUNKNOWN International Health Informatics Study (IHIS) Network
Aug 27, 2019·The Application of Clinical Genetics·Maria Mariana Barros Melo da SilveiraDário Celestino Sobral Filho
Jun 9, 2020·Circulation. Genomic and Precision Medicine·Chengxian GuoGuoping Yang